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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • MYL3 Antibodies

          Invitrogen

          MYL3 Polyclonal Antibody

          View all (16) MYL3 antibodies

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          Cite MYL3 Polyclonal Antibody

          • Antibody Testing Data (2)
          MYL3 Antibody in Western Blot (WB)
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          MYL3 Antibody in Western Blot (WB)
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          MYL3 Antibody (PA5-27819) in WB

          Western Blot using MYL3 Polyclonal Antibody (Product # PA5-27819). Sample (50 µg of whole cell lysate). Lane A: mouse heart. 12% SDS PAGE. MYL3 Polyclonal Antibody (Product # PA5-27819) diluted at 1:10,000. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          MYL3 Antibody in Western Blot (WB)
          MYL3 Antibody in Western Blot (WB)

          Product Details

          PA5-27819

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:1,000-1:10,000
          -
          Product Specifications

          Species Reactivity

          Human, Mouse

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein encompassing a sequence within the center region of human Myosin Light Chain 3. The exact sequence is proprietary.

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.52 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          0.1M tris glycine, pH 7, with 10% glycerol

          Contains

          0.01% thimerosal

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2545295

          Product Specific Information

          Recommended positive controls: Molt-4, mouse heart.

          Predicted reactivity: Mouse (91%), Rat (93%), Xenopus laevis (80%), Pig (97%), Chicken (86%), Bovine (95%).

          Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

          Target Information

          MYL3 encodes myosin light chain 3, an alkali light chain also referred to in the literature as both the ventricular isoform and the slow skeletal muscle isoform. Mutations in MYL3 have been identified as a cause of mid-left ventricular chamber type hypertrophic cardiomyopathy.

          ⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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          Cite this product

          Bioinformatics

          Protein Aliases: Cardiac myosin light chain 1; CMLC1; MLC-lV/sb; MLC1SB; Myosin alkali light chain 1, ventricular/slow skeletal muscle isoform; Myosin light chain 1, slow-twitch muscle B/ventricular isoform; Myosin light chain 3; myosin light chain, alkali, cardiac ventricles; myosin, light chain 3, alkali; ventricular, skeletal, slow; myosin, light polypeptide 3, alkali; ventricular, skeletal, slow; slow skeletal; ventricular; Ventricular myosin alkali light chain; Ventricular myosin light chain 1; Ventricular/slow twitch myosin alkali light chain; VLCl

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          Gene Aliases: CMH8; MLC-lV/sb; MLC1s; MLC1SB; MLC1V; MYL3; Mylc; VLC1; VLCl

          View more View less

          UniProt ID: (Human) P08590, (Mouse) P09542

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          Entrez Gene ID: (Human) 4634, (Mouse) 17897

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          Function(s)
          motor activity actin monomer binding calcium ion binding structural constituent of muscle myosin II heavy chain binding
          Process(es)
          regulation of the force of heart contraction regulation of striated muscle contraction skeletal muscle tissue development muscle filament sliding positive regulation of ATPase activity ventricular cardiac muscle tissue morphogenesis cardiac muscle contraction metabolic process
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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