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Invitrogen
MYL9/MYL12 Recombinant Rabbit Monoclonal Antibody (AWBMyl9F6 (F-6))
Product Details
MA5-27983
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG, kappa
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
AWBMyl9F6 (F-6)
Immunogen
N-terminal peptide of Myl9
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A/G
Storage buffer
PBS, pH 7.4, with 0.1% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2744997
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
Target Information
Myosin regulatory light polypeptide 9 is a highly conserved, ubiquitously expressed protein that in humans is encoded by the MYL9 gene. Myosin, a structural component of muscle, are hexameric proteins consisting of two heavy chains and four light chains, including a single pair of nonphosphorylatable light chain subunits and another pair of phosphorylatable light chain subunits.The protein encoded by this gene is a myosin light chain that may regulate muscle contraction by modulating the ATPase activity of myosin heads. Myosin light chain (Myl) 9 and Myl12 are new functional ligands for CD69. Blockade of CD69-Myl9/12 interactio ameliorates allergic airway inflammation in ovalbumin-induced and house dust mite-induced mouse models of asthma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 20 kDa myosin light chain; brain specific myosin regulatory light chain; Epididymis secretory protein Li 24; HEL-S-24; LC20; MLC-2; MLC-2A; MLC-2B; MLC-2C; MLC20; myosin light chain, regulatory B; myosin light chain, regulatory B-like; myosin light chain, regulatory C; myosin regulatory light chain 1; Myosin regulatory light chain 12A; Myosin regulatory light chain 12B; myosin regulatory light chain 2; Myosin regulatory light chain 2, nonsarcomeric; Myosin regulatory light chain 2, smooth muscle isoform; Myosin regulatory light chain 2-B, smooth muscle isoform; Myosin regulatory light chain 20 kDa; myosin regulatory light chain 3; Myosin regulatory light chain 9; Myosin regulatory light chain MRLC1; Myosin regulatory light chain MRLC2; Myosin regulatory light chain MRLC3; Myosin regulatory light polypeptide 9; Myosin RLC; myosin, light chain 12A, regulatory, non-sarcomeric; myosin, light chain 12B, regulatory; myosin, light chain 9, regulatory; myosin, light polypeptide 9, regulatory; myosin, light polypeptide, regulatory, non-sarcomeric (20kD); NMDA receptor-interacting protein; SHUJUN-1
Gene Aliases: 1500001M02Rik; 2900073G15Rik; AI327049; AI838292; C77744; C80200; HEL-S-24; LC20; MLC-2B; MLC-2C; MLC-B; MLC2; MLC20; MLCB; MRCL3; MRLC1; MRLC2; MRLC3; MYL12A; MYL12B; MYL2B; MYL9; MYLC2B; Mylc2c; MYRL2; RLC; RLC-B; RLC-C
UniProt ID: (Human) P19105, (Human) O14950, (Human) P24844, (Mouse) Q3THE2, (Mouse) Q9CQ19
Entrez Gene ID: (Human) 10627, (Human) 103910, (Human) 10398, (Mouse) 67268, (Mouse) 67938, (Mouse) 98932
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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