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Invitrogen
MYO1B Recombinant Rabbit Monoclonal Antibody (JE65-01)
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FIGURE: 1 / 4
MYO1B Antibody (MA5-50668) in IHC (P)
Immunohistochemistry of MYO1B in paraffin-embedded human colon carcinoma tissue. The section was pre-treated using heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0) for 20 minutes. The tissues were blocked in 1% BSA for 20 minutes at room temperature, washed with ddH2O and PBS, and then probed with MYO1B recombinant monoclonal antibody (Product # MA5-50668) with a dilution of 1:400 for 1 hour a... View More
Product Details
MA5-50668
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
JE65-01
Immunogen
Recombinant protein within human MYO1B aa 916-1136/1136.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
TBS, pH 7.4, with 0.05% BSA, 40% glycerol
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_3093800
Product Specific Information
Positive control: A431 cell lysate, NIH/3T3 cell lysate, human lymph nodes tissue, human testis tissue, human colon carcinoma tissue.
Predicted band size: 132 kDa
Subcellular Location: Actin cytoskeleton, actin filament, myosin complex, early endosome, endosome membrane, extracellular exosome, plasma membrane, apical part of cell, brush border, cell periphery, cytoplasm, filopodium, microvillus, perinuclear region of cytoplasm, vesicle.
Target Information
Motor protein that may participate in process critical to neuronal development and function such as cell migration, neurite outgrowth and vesicular transport.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: MIH-L; MMI-alpha; MMIa; molecular motor; MYH-1c; MYO1B variant protein; Myosin I alpha; Myosin IA (Myosin I alpha) (MMI-alpha) (MMIa) (MIH-L); myosin-I alpha; myosin-Ib; Unconventional myosin-Ib
Gene Aliases: AA406997; MIH-L; MMIa; MYO1B; myr1
UniProt ID: (Human) O43795, (Mouse) P46735
Entrez Gene ID: (Human) 4430, (Mouse) 17912
microfilament motor activity
calmodulin binding
ATP binding
phosphatidylinositol-4,5-bisphosphate binding
phosphatidylinositol-3,4,5-trisphosphate binding
actin-dependent ATPase activity
actin filament binding
cadherin binding involved in cell-cell adhesion
nucleotide binding
motor activity
actin binding
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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