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Antibody detects endogenous levels of total MYO3B.
MYO3B (MYO3 beta) is a member of the Class III myosins that are actin-dependent motor proteins containing an amino-terminal kinase domain. MYO3B contains a N-terminal kinase domain, followed by motor, neck, and tail domains. The MYO3B gene generates a variety of splice variants that contain 1 or 2 calmodulin-binding (IQ) motifs in the neck domain and 1 of 3 domains in the tail domain. Northern blot analysis shows expression of a 7-kb MYO3B transcript in the human retina but not in a RPE cell line. The MYO3B gene transcript is also detected in the kidney, intestine and testis. The MYO3B gene maps to chromosome 2q31.1-q31.2 by genomic sequence alignment.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: myosin IIIB1; myosin IIIB2; Myosin-IIIb
Gene Aliases: A430065P19Rik; MYO3B
UniProt ID: (Human) Q8WXR4, (Mouse) Q1EG27
Entrez Gene ID: (Human) 140469, (Mouse) 329421
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