Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: EFKTLSEQLS VTTSTYTMEV ERLKKELVHY QQSPGEDTSL RLQEEVESLR TELQRAHSER KILEDAHSRE KDELRKRVAD LEQENALLKD EKEQLNNQIL CQSKDEFAQN SVKENLMKKE LEEERSRYQN LVKEYSQLEQ RYDNLRDEMT IIKQTPGHRR NPSNQSSLES DSNYP
May be involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation. Required in a complex with RAB11A and RAB11FIP2 for the transport of NPC1L1 to the plasma membrane. Together with RAB11A participates in CFTR trafficking to the plasma membrane and TF (transferrin) recycling in nonpolarized cells. Together with RAB11A and RAB8A participates in epithelial cell polarization. Together with RAB25 regulates transcytosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: MYO5B variant protein; myosin 5B; Myosin heavy chain myr 6; Myosin of the dilute-myosin-V family; myosin-Vb; Unconventional myosin-Vb
Gene Aliases: AI661750; KIAA1119; mKIAA1119; MYO5B; Myr6
UniProt ID: (Human) Q9ULV0, (Rat) P70569
Entrez Gene ID: (Human) 4645, (Mouse) 17919, (Rat) 25132
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn moreGet expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support