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Immunogen sequence: STQASSQKSL SQRSSSQRAS SQTSLGGTIC RVCAKRVSTQ EDEEQENRSR YQSLVAAYGE AKRQRFLSEL AHLEEDVHLA RSQARDKLDK YAIQQMMEDK LAWERHTFEE RISRAPEILV RLRSHTVWER MSVKLCFTVQ GF
Highest antigen sequence identity to the following orthologs: Mouse - 75%, Rat - 71%.
The giant protein titin, together with its associated proteins, interconnects the major structure of sarcomeres, the M bands and Z discs. The C-terminal end of the titin string extends into the M line, where it binds tightly to M-band constituents of apparent molecular masses of 190 kD and 165 kD. The predicted MYOM2 protein contains 1,465 amino acids. Like MYOM1, MYOM2 has a unique N-terminal domain followed by 12 repeat domains with strong homology to either fibronectin type III or immunoglobulin C2 domains. Protein sequence comparisons suggested that the MYOM2 protein and bovine M protein are identical. [provided by RefSeq, Jul 2008].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 165 kDa connectin-associated protein; 165 kDa titin-associated protein; M-band protein; M-protein; myomesin (M-protein) 2, 165kDa; Myomesin family member 2; Myomesin-2; titin-associated protein, 165 kD
Gene Aliases: MYOM2; TTNAP
UniProt ID: (Human) P54296
Entrez Gene ID: (Human) 9172
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