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Product Details
17692-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
MYOM3 Fusion Protein Ag11849 (888-1213 aa encoded by BC067101)
Conjugate
Form
Liquid
Concentration
0.27 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
This antibody recognizes the intact MYOM3 protein (160-160 kDa) as well as MYOM3 fragments (100 kDa and 130 kDa).
Immunogen sequence: SMPTDPVLL EDKPGAHEIE VGVDEEGFIY LAFEAPEAPD SSEFQWSKDY KGPLDPQRVK IEDKVNKSKV ILKEPGLEDL GTYSVIVTDA DEDISASHTL TEEELEKLKK LSHEIRNPVI KLISGWNIDI LERGEVRLWL EVEKLSPAAE LHLIFNNKEI FSSPNRKINF DREKGLVEVI IQNLSEEDKG SYTAQLQDGK AKNQITLTLV DDDFDKLLRK ADAKRRDWKR KQGPYFERPL QWKVTEDCQV QLTCKVTNTK KETRFQWFFQ RAEMPDGQYD PETGTGLLCI EEASVAPASG LTFSFGCKPG RAKSSGLGVR AGPRLG (888-1213 aa encoded by BC067101 )
Target Information
MYOM3 (myomesin 3) is a structural component of the M-band in striated muscle and is involved in sarcomere stability and resistance during intense or sustained stretching. MYOM3 can be detected mainly in intermediate speed fibers of skeletal muscle. Recently high level of MYOM3 fragments were detected in sera from patients with muscular dystrophy, including Duchenne muscular dystrophy (DMD). MYOM3 fragments may be used as serum biomarker for DMD and other neuromuscular disorders.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Myomesin family member 3; myomesin family, member 3; Myomesin-3
Gene Aliases: 8430427K15Rik; Gm434; MYOM3
UniProt ID: (Human) Q5VTT5, (Mouse) A2ABU4
Entrez Gene ID: (Human) 127294, (Mouse) 242702
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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