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Invitrogen
MYOM3 Polyclonal Antibody
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MYOM3 Antibody (PA5-100627) in IHC (P)
Immunohistochemistry analysis of MYOM3 in mouse heart tissue. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with MYOM3 polyclonal antibody (Product # PA5-100627) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
Product Details
PA5-100627
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human MYOM3(Accession Q5VTT5), corresponding to amino acid residues N1089-T1139.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2850134
Product Specific Information
Antibody detects endogenous levels of total MYOM3.
Target Information
MYOM3 (myomesin 3) is a structural component of the M-band in striated muscle and is involved in sarcomere stability and resistance during intense or sustained stretching. MYOM3 can be detected mainly in intermediate speed fibers of skeletal muscle. Recently high level of MYOM3 fragments were detected in sera from patients with muscular dystrophy, including Duchenne muscular dystrophy (DMD). MYOM3 fragments may be used as serum biomarker for DMD and other neuromuscular disorders.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Myomesin family member 3; myomesin family, member 3; Myomesin-3
Gene Aliases: 8430427K15Rik; Gm434; MYOM3
UniProt ID: (Human) Q5VTT5, (Mouse) A2ABU4
Entrez Gene ID: (Human) 127294, (Mouse) 242702
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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