Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Abnova
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Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MSLENEDKRA RTRSKALRGP PETTAADLSC PTPGCTGSGH VRGKYSRHRS LQSCPLAKKR KLEGAEAEHL VSKRKSHPLK LALDEGYGVD SDGSEDTEVK DASVSDESEG TLEGAEAETS GQDEIHRPET AEGRSPVKSH FGSNPIGSAT ASSKGSYSSY QGIIATSLLN LGQIAEETLV EEDLGQAAKP GPGIVHLLQE AAEGAASEEG EKGLFIQPED AEEVVEVTTE RSQDLCPQSL EDAASEESSK QKGILSHEEE DEEEEEEEEE EEEDEEEEEE EEEEEEEEEE EEEEEEEEEE EEEEEEAAPD VIFQEDTSHT SAQKAPELRG PESPSPKPEY SVIVEVRSDD DKDEDTHSRK STVTDESEMQ DMMTRGNLGL LEQAIALKAE QVRTVCEPGC PPAEQSQLGL GEPGKAAKPL DTVRKSYYSK DPSRAEKREI KCPTPGCDGT GHVTGLYPHH RSLSGCPHKD RIPPEILAMH ENVLKCPTPG CTGQGHVNSN RNTHRSLSGC PIAAAEKLAK SHEKQQPQTG DPSKSSSNSD RILRPMCFVK QLEVPPYGSY RPNVAPATPR ANLAKELEKF SKVTFDYASF DAQVFGKRML APKIQTSETS PKAFQCFDYS QDAEAAHMAA TAILNLSTRC WEMPENLSTK PQDLPSKSVD IEVDENGTLD LSMHKHRKRE NAFPSSSSCS SSPGVKSPDA SQRHSSTSAP SSSMTSPQSS QASRQDEWDR PLDYTKPSRL REEEPEESEP AAHSFASSEA DDQEVSEENF EERKYPGEVT LTNFKLKFLS KDIKKELLTC PTPGCDGSGH ITGNYASHRS LSGCPLADKS LRNLMAAHSA DLKCPTPGCD GSGHITGNYA SHRSLSGCPR AKKSGVKVAP TKDDKEDPEL MKCPVPGCVG LGHISGKYAS HRSASGCPLA ARRQKEGSLN GSSFSWKSLK NEGPTCPTPG CDGSGHANGS FLTHRSLSGC PRATFAGKKG KLSGDEVLSP KFKTSDVLEN DEEIKQLNQE IRDLNESNSE MEAAMVQLQS QISSMEKNLK NIEEENKLIE EQNEALFLEL SGLSQALIQS LANIRLPHME PICEQNFDAY VSTLTDMYSN QDPENKDLLE SIKQAVRGIQ V
The protein encoded by this gene is a member of a family of neural specific, zinc finger-containing DNA-binding proteins. This kinase preferentially phosphorylates and inactivates cell division cycle 2 protein (CDC2), and thus negatively regulates cell cycle G2/M transition. This kinase is associated with the membrane throughout the cell cycle. Its activity is highly regulated during the cell cycle. Protein kinases AKT1/PKB and PLK (Polo-like kinase) have been shown to phosphorylate and regulate the activity of this kinase. Alternatively spliced transcript variants encoding distinct isoforms have been reported. The protein binds to the promoter regions of proteolipid proteins of the central nervous system and plays a role in the developing nervous system.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Myelin transcription factor 1; Myelin transcription factor I; MyT1; MyTI; neural zinc finger transcription factor 2; PLPB1; proteolipid protein binding protein; Proteolipid protein-binding protein
Gene Aliases: C20orf36; KIAA0835; KIAA1050; MTF1; MYT1; MYTI; NZF2; PLPB1; ZC2H2C1; ZC2HC4A
UniProt ID: (Human) Q01538
Entrez Gene ID: (Human) 4661
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