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Invitrogen
MZB1 Polyclonal Antibody
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MZB1 Antibody (PA5-21794) in IHC (P)
PACAP Polyclonal Antibody detects PACAP protein at cytosol on human normal colon mucosa with lymphocyte by immunohistochemical analysis. Sample: Paraffin-embedded normal colon mucosa with lymphocyte. PACAP Polyclonal Antibody (Product # PA5-21794) dilution: 1:500.
Product Details
PA5-21794
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human PACAP. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
0.48 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 10% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_11152981
Product Specific Information
Recommended positive controls: Molt-4, Raji.
Predicted reactivity: Rhesus Monkey (97%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
MZB1 associates with immunoglobulin M (IgM) heavy and light chains and promotes IgM assembly and secretion. May exert its effect by acting as a molecular chaperone or as an oxidoreductase as it displays a low level of oxidoreductase activity. Isoform 2 may be involved in regulation of apoptosis. Helps to diversify peripheral B-cell functions by regulating Ca(2+) stores, antibody secretion and integrin activation.; Acts as a hormone-regulated adipokine/proinflammatory cytokine that is implicated in causing chronic inflammation, affecting cellular expansion and blunting insulin response in adipocytes. May have a role in the onset of insulin resistance.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: caspase-2 binding protein; HSPC190; marginal zone B and B1 cell-specific protein; Marginal zone B- and B1-cell-specific protein; MEDA-7; Mesenteric estrogen-dependent adipose 7; mesenteric oestrogen-dependent adipose gene- 7; MGC29506; plasma cell-induced ER protein 1; Plasma cell-induced resident endoplasmic reticulum protein; Plasma cell-induced resident ER protein; Proapoptotic caspase adapter protein; proapoptotic caspase adaptor protein
Gene Aliases: 2010001M09Rik; AV064572; HSPC190; MEDA-7; MEDA7; MZB1; PACAP; pERp1
UniProt ID: (Human) Q8WU39, (Mouse) Q9D8I1
Entrez Gene ID: (Human) 51237, (Mouse) 69816
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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