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MZF1 Antibody (PA5-106478) in ICC/IF
Immunocytochemistry analysis of MZF1 in A549 cells. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with MZF1 polyclonal antibody (Product # PA5-106478) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG(H+L) (Red) and an AlexaFluor488 conjugated goat anti-mouse IgG(H+L) (Green) were used as the secondary antibodies. The nuclear counter stain is DAPI (blue).
Product Details
PA5-106478
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human MZF1(Accession P28698), corresponding to amino acid residues M1-P40.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2854147
Product Specific Information
Antibody detects endogenous levels of total MZF-1.
Target Information
Binds to target promoter DNA and functions as transcription regulator. Regulates transcription from the PADI1 and CDH2 promoter. May be one regulator of transcriptional events during hemopoietic development. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Myeloid zinc finger 1; Myeloid zinc finger protein 1; Myeloid zinc finger protein 2; myeloid-specific retinoic acid-responsive zinc finger protein; MZF-1; Zinc finger and SCAN domain-containing protein 6; zinc finger protein 121; Zinc finger protein 42; zinc finger protein 42 (myeloid-specific retinoic acid-responsive); zinc finger protein 98
Gene Aliases: MZF; MZF-1; Mzf-2; MZF1; MZF1B; Mzf2; Zfp121; ZFP98; ZNF42; ZSCAN6
UniProt ID: (Human) P28698
Entrez Gene ID: (Human) 7593, (Mouse) 109889, (Rat) 361508
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
protein binding
protein homodimerization activity
transcription regulatory region DNA binding
metal ion binding
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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