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Invitrogen
Marburg Virus Nucleoprotein Monoclonal Antibody (3544)
Product Details
MA5-47505
Product Specifications
Species Reactivity
Virus
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
3544
Immunogen
Proprietary sequence
Conjugate
Form
Liquid
Concentration
100 µg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.2
Contains
0.1% sodium azide
Storage conditions
4°C
Shipping conditions
Wet ice
RRID
AB_2942486
Product Specific Information
Specificity: Specific for the NP antigen of the virus. Reactive with several native strains. Negative for EBOLA. Non-reactive with mammalian cells (ICC/IF).
Purified preparations consist of >90% pure mouse monoclonal antibody which has been purified from ascites fluid by protein A chromatography. The final preparation is formulated to a protein concentration of 100 µg/mL in 0.01 M phosphate buffered saline, pH 7.2 and contains 0.1% sodium azide. Each vial contains 1.0 mL. This product contains no stabilizing proteins and should be stored at 4C until ready for use. Working dilution must be determined by the user. Suggested starting ranges are 1:10-1:50 for ICC/IF and 1:20-1:200. for ELISA.
Target Information
Marburg virus (MBG) is a representative of Filoviridae family of RNA containing viruses. MBG is an exceptionally dangerous pathogen, which induces a severe contagious and highly lethal (53-88%) febrile disease with hemorrhagic syndrome. The name ""thread viruses"" is based on their morphology. MBG made its appearance in 1967 in the form of frightening nosocomial outbreak, initially among polio vaccine production workers in Germany in contact with Ugandan green monkeys and their kidney tissues. The patho-and immuno-genesis of MBG fever have so far been little studied, no specific agents or treatment methods have been developed. The nucleoprotein encapsidates the viral genomic RNA by oligomerization and form a ribonucleoprotein complex.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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