Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Reconstitute in distilled water.
Measles virus (MeV) is an enveloped RNA virus in the Morbillivirus genus of the Paramyxoviridae family. Its non- segmented, negative-sense, single- stranded RNA genome is encapsidated by the viral nucleoprotein (N) within a helical nucleocapsid. Transcription and replication are carried out on this N:RNA complex by the viral polymerase complex which consists of two components, the large protein (L) and the phosphoprotein (P). MeV N consists of two regions: a structured N-terminal moiety, NCORE, which contains all the regions necessary for self-assembly and RNA-binding, and a C-terminal domain, NTAIL that is intrinsically unstructured and is exposed at the surface of the viral nucleocapsid.
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