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Alomone Labs, LTD
Melatonin Receptor 1A (MTNR1A) Polyclonal Antibody
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FIGURE: 1 / 2
Melatonin Receptor 1A (MTNR1A) Antibody (AMR-031-200UL) in IHC
Expression of Melatonin receptor type 1A in rat supra-chiasmatic nucleus - Immunohistochemical staining of rat supra-chiasmatic nucleus (SCN) with Anti-Melatonin Receptor 1A (MTNR1A) Antibody (#AMR-031). A. MT1 staining is restricted to the SCN (red). B. DAPI is used as the counterstain (blue). C. Merge of A and B.
Product Details
AMR-031-200UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
(C)RVKPDNKPKLKPQD, corresponding to amino acid residues 223-236 of mouse MTNR1A, 3rd intracellular loop
Conjugate
Form
Lyophilized
Concentration
0.8 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 1% BSA
Contains
0.05% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
Target Information
This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This receptor is a G-protein coupled, 7-transmembrane receptor that is responsible for melatonin effects on mammalian circadian rhythm and reproductive alterations affected by day length. The receptor is an integral membrane protein that is readily detectable and localized to two specific regions of the brain. The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Mel-1A-R; mel1a melatonin receptor; Mel1a receptor; Melatonin receptor type 1A
Gene Aliases: MelR; MR; Mtnr1a
UniProt ID: (Mouse) Q61184
Entrez Gene ID: (Mouse) 17773, (Rat) 114211
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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