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Bioss
Metabotropic Glutamate Receptor 4/6 Polyclonal Antibody
Product Details
BS-1894R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human Metabotropic Glutamate Receptor 4.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: G protein-coupled receptor GRM4; G protein-coupled receptor GRM6; G protein-coupled receptor, family C, group 1, member D; G protein-coupled receptor, family C, group 1, member F; glutamate receptor, metabotropic 4; glutamate receptor, metabotropic 6; Metabotropic glutamate receptor 4; Metabotropic glutamate receptor 6; mGluR4; mGluR6
Gene Aliases: BC021919; CSNB1B; Gm3; GPRC1D; GPRC1F; GRM4; GRM6; mGlu4; mGlu6; MGLUR4; MGLUR6; nerg1; nob2; nob3; nob4
UniProt ID: (Human) Q14833, (Human) O15303, (Rat) P31423, (Mouse) Q68EF4, (Rat) P35349, (Mouse) Q5NCH9
Entrez Gene ID: (Human) 2914, (Human) 2916, (Rat) 24417, (Mouse) 268934, (Rat) 24419, (Mouse) 108072
group III metabotropic glutamate receptor activity
G-protein coupled receptor activity
glutamate receptor activity
protein binding
protein homodimerization activity
calmodulin binding
calcium-dependent protein binding
signal transducer activity
adenylate cyclase inhibiting G-protein coupled glutamate receptor activity
activation of MAPK activity
adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway
chemical synaptic transmission
learning
negative regulation of cell proliferation
gamma-aminobutyric acid secretion
neuron projection development
synaptic transmission, glutamatergic
negative regulation of apoptotic process
positive regulation of MAPK cascade
regulation of neuron apoptotic process
negative regulation of synaptic transmission
synaptic transmission, GABAergic
regulation of synaptic transmission, glutamatergic
signal transduction
G-protein coupled glutamate receptor signaling pathway
locomotory behavior
detection of light stimulus involved in visual perception
sensory perception of light stimulus
retina development in camera-type eye
positive regulation of calcium ion import
G-protein coupled receptor signaling pathway
visual perception
response to stimulus
detection of visible light
neurotransmitter secretion
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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