Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
Mig-6 Polyclonal Antibody
Promotion
View available promotion(s)
Promo code: {{promo.promoCode}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Product Details
PA5-31137
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human Mig-6. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
0.65 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 1% BSA, 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2548611
Product Specific Information
Recommended positive controls: HCT116.
Predicted reactivity: Rhesus Monkey (99%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
ERRFI1 is a cytoplasmic protein whose expression is upregulated with cell growth (Wick et al., 1995). It shares significant homology with the protein product of rat gene-33, which is induced during cell stress and mediates cell signaling (Makkinje et al., 2000).
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: ERBB receptor feedback inhibitor 1; MIG-6; Mitogen-inducible gene 6 protein; Mitogen-inducible gene 6 protein homolog; receptor-associated late transducer
Gene Aliases: 1300002F13Rik; AI788755; ERRFI1; GENE-33; MIG-6; MIG6; RALT
UniProt ID: (Human) Q9UJM3, (Mouse) Q99JZ7
Entrez Gene ID: (Human) 54206, (Mouse) 74155
negative regulation of epidermal growth factor-activated receptor activity
stress-activated protein kinase signaling cascade
negative regulation of protein autophosphorylation
negative regulation of interleukin-1 beta production
negative regulation of collagen biosynthetic process
negative regulation of epidermal growth factor receptor signaling pathway
negative regulation of tumor necrosis factor biosynthetic process
skin morphogenesis
regulation of keratinocyte differentiation
lung alveolus development
negative regulation of peptidyl-tyrosine phosphorylation
lung vasculature development
lung epithelium development
regulation of type B pancreatic cell proliferation
negative regulation of ERK1 and ERK2 cascade
negative regulation of cardiac muscle hypertrophy in response to stress
response to stress
cellular response to insulin stimulus
cellular response to platelet-derived growth factor stimulus
positive regulation of GTPase activity
cellular response to epidermal growth factor stimulus
cellular hyperosmotic response
cellular response to dexamethasone stimulus
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support