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Invitrogen
Mimecan Polyclonal Antibody
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Product Details
PA5-53019
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human Mimecan. Recombinant protein control fragment (Product #RP-89834).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2643974
Product Specific Information
Immunogen sequence: SLLEELSLAE NQLLKLPVLP PKLTLFNAKY NKIKSRGIKA NAFKKLNNLT FLYLDHNALE SVPLNLPESL RVIHLQFNNI ASITDDTFCK ANDTSYIRDR IEEIRLEGNP IVLGKHPNSF I
Highest antigen sequence identity to the following orthologs: Mouse - 87%, Rat - 88%.
Target Information
Mimecan induces ectopic bone formation in conjunction with transforming growth factor beta. Mimecan is a small proteoglycan which contains tandem leucine-rich repeats. Mimecan is encoded by the OGN gene, a member of the small leucine-rich proteoglycan (SLRP) family of proteins. Mimecan induces ectopic bone formation in conjunction with transforming growth factor beta (TGF-beta-1 or TGF-beta-2) and may regulate osteoblast differentiation. High expression of mimecan protein may be associated with elevated heart left ventricular mass. Alternative splicing results in multiple transcript variants of mimecan. Alternatively spliced transcript variants that encode mimecan have been found.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: corneal keratan sulfate proteoglycan; Mimecan; mimecan proteoglycan; OIF; Osteoglycin; Osteoinductive factor
Gene Aliases: OG; OGN; OIF; SLRR3A
UniProt ID: (Human) P20774
Entrez Gene ID: (Human) 4969
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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