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Invitrogen
Monoacylglycerol Lipase Polyclonal Antibody
FIGURE: 1 / 4
Monoacylglycerol Lipase Antibody (PA5-121021) in IHC (P)
Immunohistochemistry analysis of Monoacylglycerol Lipase in paraffin-embedded mouse kidney. Samples were incubated with Monoacylglycerol Lipase Polyclonal antibody (Product # PA5-121021) using a dilution of 1:50 (40x lens). Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.
Product Details
PA5-121021
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 11-313 of human MGLL (NP_0092141)
Conjugate
Form
Liquid
Concentration
1.69 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2914593
Product Specific Information
Positive test controls include: HepG2, A-549, SH-SY5Y, Mouse heart, Rat brain, Rat heart. The target is usually found in the following locations: Cytoplasm, Membrane, Peripheral membrane protein, cytosol.
Immunogen sequence: MPEESSPRRT PQSIPYQDLP HLVNADGQYL FCRYWKPTGT PKALIFVSHG AGEHSGRYEE LARMLMGLDL LVFAHDHVGH GQSEGERMVV SDFHVFVRDV LQHVDSMQKD YPGLPVFLLG HSMGGAIAIL TAAERPGHFA GMVLISPLVL ANPESATTFK VLAAKVLNLV LPNLSLGPID SSVLSRNKTE VDIYNSDPLI CRAGLKVCFG IQLLNAVSRV ERALPKLTVP FLLLQGSADR LCDSKGAYLL MELAKSQDKT LKIYEGAYHV LHKELPEVTN SVFHEINMWV SQRTATAGTA SPP
Target Information
Monoglyceride lipase functions together with hormone-sensitive lipase to hydrolyze intracellular triglyceride stores in adipocytes and other cells to fatty acids and glycerol. MGLL may also complement lipoprotein lipase in completing hydrolysis of monoglycerides resulting from degradation of lipoprotein triglycerides.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: HU-K5; Lysophospholipase homolog; Lysophospholipase-like; MAGL; MGL; Monoacylglycerol lipase; Monoglyceride lipase
Gene Aliases: AA589436; HU-K5; HUK5; MAGL; MGL; Mgl2; MGLL
UniProt ID: (Human) Q99685, (Rat) Q8R431, (Mouse) O35678
Entrez Gene ID: (Human) 11343, (Rat) 29254, (Mouse) 23945
fatty acid biosynthetic process
regulation of signal transduction
arachidonic acid metabolic process
triglyceride catabolic process
regulation of axon extension
acylglycerol catabolic process
regulation of inflammatory response
regulation of sensory perception of pain
long term synaptic depression
regulation of endocannabinoid signaling pathway
lipid metabolic process
inflammatory response
acylglycerol acyl-chain remodeling
fatty acid metabolic process
lipid catabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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