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Invitrogen
Monoamine Oxidase B Recombinant Rabbit Monoclonal Antibody (JG39-97)
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Product Details
MA5-34805
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
JG39-97
Immunogen
Synthetic peptide within Human Monoamine Oxidase B aa 1-126
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
TBS, pH 7.4, with 40% glycerol, 0.05% BSA
Contains
0.05% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles, store in dark
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2848713
Product Specific Information
Positive Control: Human liver tissue, human prostate cancer tissue, human kidney tissue.
Target Information
MAOB (Monoamine Oxidase B), also called MAO, BRAIN, AMINE OXIDASE (FLAVIN-CONTAINING) B, is a protein that in humans is encoded by the MAOB gene. MAOB is a member of the flavin monoamine oxidase family. And it is mapped on Xp11.3. MAOB catalyzes the oxidative deamination of biogenic and xenobiotic amines and plays an important role in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. This protein preferentially degrades benzylamine and phenylethylamine. Like MAOA, it also degrades dopamine. MAO-B is involved in the breakdown of dopamine, a neurotransmitter implicated in reinforcing and motivating behaviors as well as movement. MAO-B inhibition is, therefore, associated with enhanced activity of dopamine, as well as with decreased production of hydrogen peroxide, a source of reactive oxygen species.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: adrenalin oxidase; Amine oxidase [flavin-containing] B; HGNC:6834; MAO b; MAO, brain; MAO, platelet; MAO-B; MGC26382; Monoamine oxidase type B; RP1-201D17__B.1; tyramine oxidase
Gene Aliases: MAOB
UniProt ID: (Human) P27338
Entrez Gene ID: (Human) 4129
response to toxic substance
response to aluminum ion
response to selenium ion
negative regulation of serotonin secretion
substantia nigra development
response to lipopolysaccharide
dopamine catabolic process
response to drug
response to ethanol
positive regulation of dopamine metabolic process
hydrogen peroxide biosynthetic process
response to corticosterone
oxidation-reduction process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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