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GenScript
Mosunetuzumab Recombinant Rabbit Monoclonal Antibody (38A10), MonoRab™
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FIGURE: 1 / 5
Mosunetuzumab Antibody (A02291-40) in ELISA
Left Figure: Standard Curve of Mosunetuzumab Sandwich ELISA by A02290 (4G6) and A02291 (38A10). In this Sandwich ELISA assay, MonoRab™ Anti-Mosunetuzumab Antibody (4G6), mAb, Rabbit (GenScript, A02290) was coated at a concentration of 1 μg/mL, and MonoRab™ Anti-Mosunetuzumab Antibody (38A10), mAb, Rabbit (GenScript, A02291) conjugated with Biotin was used as a detection antibody at a concentration of 0.4 μg/mL. MRD was as 1:25. In this assay, a four-parameter logistic curve fitting program was used to create a standard curve with the R-Squ... View More
Product Details
A02291-40
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG, kappa
Expression System
Mammalian cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
38A10
Immunogen
Mosunetuzumab
Conjugate
Form
Lyophilized
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.2
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitute the lyophilized antibody with deionized water (or equivalent) to a final concentration of 0.5 mg/mL.
Sandwich ELISA recommended dilution: 0.4-2 µg/mL; Competitive ELISA recommended dilution: 1-10 µg/mL
The lyophilized product remains stable up to 1 year at -20 °C from date of receipt. Upon reconstitution, it can be stored for 2-3 weeks at 2-8 °C or for up to 12 months at -20 °C or below. Avoid repeated freezing and thawing cycles.
Target Information
Mosunetuzumab is an investigational, humanized, T-cell bispecific antibody designed to engage T cells and redirect their cytotoxic activity against malignant B cells. Mosunetuzumab simultaneously binds to CD3 epsilon (CD3epsilon), a component of the T-cell receptor (TCR) complex, and to CD20, a B-cell surface protein expressed in a majority of B-cell malignancies. This results in crosslinking of the TCR, inducing downstream signaling events that lead to B-cell killing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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