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Invitrogen
Muromonab Chimeric Recombinant Rabbit Monoclonal Antibody (OKT-3 (muromonab))
FIGURE: 1 / 1
Muromonab Chimeric Antibody (MA5-47769) in ICC/IF
Immunocytochemistry/Immunofluorescence analysis of Muromonab in Molt4 cells using Muromonab Chimeric Monoclonal Antibody (Product # MA5-47769). Paraformaldehyde-fixed cells were immobilized on cover slips and stained with Muromonab Chimeric Monoclonal Antibody at 10 µg/mL for 1h followed by Alexa Fluor488 secondary antibody (1 µg/mL), showing membrane staining. The nuclear stain is DAPI (blue). Panels show ... View More
Product Details
MA5-47769
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG, kappa
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
OKT-3 (muromonab)
Immunogen
Human peripheral E+ cells.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS
Contains
0.02% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_3074219
Product Specific Information
Specificity: Epitope on the epsilon-subunit within the human CD3 complex.
Target Information
Murine monoclonal antibody specific to CD3 T-cell lymphocyte antigens. More specifically it is a purified murine (mouse) monoclonal antibody, directed against the CD3 (T3) receptor on the surface of human T-cells (T-lymphocytes) cultured using the murine ascites method. Muromonab is 93% monomeric immune globulin G type 2a (IgG2a). Muromonab binds to the T-cell surface glycoprotein CD3 epsilon chain. It appears to kill CD-3 positive cells by inducing Fc mediated apoptosis, antibody mediated cytotoxicity and complement-dependent cytotoxicity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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