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Bioss
Musashi 1/2 Polyclonal Antibody
Product Details
BS-11201R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human Musashi 1.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Musashi1 (Msi1) is an RNA-binding protein expressed in neural progenitor cells and neural stem cells. Msi1 is the mammalian homolog of Drosophila Musashi. The gene encoding human Msi1 encodes a 362 amino acid protein. In murine embryonic neural progenitor cells, Msi1 localizes to the cytoplasm and is downregulated during differentiation. Msi1 binds to NUMB, which encodes a membrane-associated antagonist of Notch signaling. Msi1 appears to function in the proliferation and maintenance of stem cell populations of the central nervous system. In addition to its usefulness as a marker for neural progenitor cells in normal human brains, Msi1 is also a marker for human gliomas. In rats, Msi1 is expressed in Sertoli cells of the testis and granulosa cells of the ovary.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Musashi homolog 1(Drosophila); Musashi homolog 2; musashi RNA-binding protein 1; musashi RNA-binding protein 2; Musashi-1; Musashi-2; musashi1; Musashi2; RNA-binding protein Musashi homolog 1; RNA-binding protein Musashi homolog 2
Gene Aliases: 1700105C15Rik; AI451722; AI563628; AW489193; m-Msi-1; MSI1; Msi1h; MSI2; MSI2H; Musahi1; RGD1560397
UniProt ID: (Human) O43347, (Human) Q96DH6, (Mouse) Q61474, (Rat) Q8K3P4, (Mouse) Q920Q6
Entrez Gene ID: (Human) 4440, (Human) 124540, (Mouse) 17690, (Rat) 259272, (Mouse) 76626, (Rat) 360596
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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