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Invitrogen
Myb Polyclonal Antibody
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Product Details
PA5-27671
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human c-Myb. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2545147
Product Specific Information
Recommended positive controls: A549, HeLa, HepG2, HCT116.
Predicted reactivity: Mouse (83%), Bovine (91%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: c-myb10A_CDS; c-myb13A_CDS; c-myb14A_CDS; c-myb8B_CDS; oncogene AMV; Proto-oncogene c-Myb; RP1-32B1.1; Transcriptional activator Myb; v-myb avian myeloblastosis viral oncogene homolog
Gene Aliases: c-myb; c-myb_CDS; Cmyb; efg; MYB
UniProt ID: (Human) P10242
Entrez Gene ID: (Human) 4602
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcription factor activity, RNA polymerase II transcription factor recruiting
protein binding
negative regulation of transcription from RNA polymerase II promoter
mitotic cell cycle
chromatin remodeling
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
positive regulation of T-helper cell differentiation
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
positive regulation of histone H3-K4 methylation
positive regulation of histone H3-K9 methylation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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