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Invitrogen
Myb Polyclonal Antibody
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FIGURE: 1 / 5
Myb Antibody (PA5-79712) in IHC (P)
Immunohistochemistry (Paraffin) analysis of Myb in paraffin-embedded section of human pancreas cancer tissue using Myb Polyclonal Antibody (Product # PA5-79712). Heat mediated antigen retrieval was performed in EDTA buffer (pH 8.0, epitope retrieval solution). The tissue section was blocked with 10% goat serum. The tissue section was then incubated with the primary antibody at a 2 µg/mL dilution overnight a... View More
Product Details
PA5-79712
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
E.coli-derived human c-Myb recombinant protein (Position: M1-E201).
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 4mg trehalose
Contains
no preservative
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2746827
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: human Jurkat whole cell, human MOLT-4 whole cell. IHC: human breast cancer, human pancrease cancer. Flow: Jurkat cell.
Target Information
Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: c-myb10A_CDS; c-myb13A_CDS; c-myb14A_CDS; c-myb8B_CDS; oncogene AMV; Proto-oncogene c-Myb; RP1-32B1.1; Transcriptional activator Myb; v-myb avian myeloblastosis viral oncogene homolog
Gene Aliases: c-myb; c-myb_CDS; Cmyb; efg; MYB
UniProt ID: (Human) P10242
Entrez Gene ID: (Human) 4602
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcription factor activity, RNA polymerase II transcription factor recruiting
protein binding
negative regulation of transcription from RNA polymerase II promoter
mitotic cell cycle
chromatin remodeling
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
positive regulation of T-helper cell differentiation
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
positive regulation of histone H3-K4 methylation
positive regulation of histone H3-K9 methylation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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