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Bethyl Laboratories
Myo18A/Myosin XVIIIA Polyclonal Antibody
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Myo18A/Myosin XVIIIA Antibody (A301-597A) in IP
Detection of human Myo18A/Myosin XVIIIA by western blot of immunoprecipitates. Samples: RIPA whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-Myo18A/Myosin XVIIIA antibody (Product # A301-597A) used for IP at 3 µg/mg lysate. Myo18A/Myosin XVIIIA was also immunoprecipitated by rabbit anti-Myo18A/Myosin XVIIIA antibody A301-598A, which recognizes a d... View More
Product Details
A301-597A
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residue 300 and 350 of human myosin 18A.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
tris citrate/phosphate, pH 7-8
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
MYO18A may link Golgi membranes to the cytoskeleton and participate in the tensile force required for vesicle budding from the Golgi. Thereby, may play a role in Golgi membrane trafficking and could indirectly give its flattened shape to the Golgi apparatus. Alternatively, in concert with LURAP1 and CDC42BPA/CDC42BPB, has been involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration. May be involved in the maintenance of the stromal cell architectures required for cell to cell contact. Regulates trafficking, expression, and activation of innate immune receptors on macrophages. Plays a role to suppress inflammatory responsiveness of macrophages via a mechanism that modulates CD14 trafficking.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: MAJN; Molecule associated with JAK3 N-terminus; myosin 18A; Myosin containing a PDZ domain; myosin containing PDZ domain; myosin-XVIIIa; SP-A receptor subunit SP-R210 alphaS; SP-R210; Surfactant protein receptor SP-R210; Unconventional myosin-XVIIIa
Gene Aliases: CD245; KIAA0216; MYO18A; MYSPDZ; SPR210; TIAF1
UniProt ID: (Human) Q92614
Entrez Gene ID: (Human) 399687
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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