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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • MYL2 Antibodies

          Proteintech

          Myosin Light Chain 2 Polyclonal Antibody

          3 References
          View all (27) MYL2 antibodies

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          Cite Myosin Light Chain 2 Polyclonal Antibody

          • Antibody Testing Data (6)
          Myosin Light Chain 2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          Myosin Light Chain 2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          FIGURE: 1 / 6

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          Myosin Light Chain 2 Antibody (55462-1-AP) in IHC (P)

          Immunohistochemistry of paraffin-embedded human skeletal muscle tissue slide using 55462-1-AP (MYL2 Antibody) at dilution of 1:50 (under 40x lens). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          Myosin Light Chain 2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Myosin Light Chain 2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Myosin Light Chain 2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Myosin Light Chain 2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Myosin Light Chain 2 Antibody in Western Blot (WB)
          Myosin Light Chain 2 Antibody in Immunoprecipitation (IP)

          Product Details

          55462-1-AP

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:2,000-1:20,000
          View 2 publications 2 publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:20-1:200
          -

          Immunocytochemistry (ICC/IF)

          -
          View 1 publication 1 publication

          Immunoprecipitation (IP)

          0.5-4.0 µg
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Published species

          Human, Mouse

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Peptide

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.79 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice (domestic); Dry ice (international)

          Target Information

          Thus gene encodes the regulatory light chain associated with cardiac myosin beta heavy chain. Ca+ triggers the phosphorylation of regulatory light chain that in turn triggers contraction. Mutations in this gene are associated with mid-left ventricular chamber type hypertrophic cardiomyopathy.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: Cardiac myosin light chain 2; cardiac myosin light chain-2; cardiac ventricular myosin light chain 2; DKFZp779C0562; MLC-2; MLC-2s/v; MLC-2v; Myosin light chain 2, slow skeletal/ventricular muscle isoform; myosin light chain 2v; myosin light chain phosphatase; myosin light chain, phosphorylatable, cardiac ventricles; myosin light chain-2; Myosin regulatory light chain 2, ventricular/cardiac muscle isoform; myosin, light chain 2, regulatory, cardiac, slow; myosin, light polypeptide 2, regulatory, cardiac, slow; regulatory light chain of myosin; RLC of myosin; slow cardiac myosin regulatory light chain 2; Ventricular myosin light chain 2; ventricular myosin regulatory light chain

          View more View less

          Gene Aliases: CMH10; MLC-2; MLC-2s/v; MLC-2v; MLC2; Mlc2v; MYL2; Mylpc

          View more View less

          UniProt ID: (Human) P10916, (Rat) P08733, (Mouse) P51667

          View more View less

          Entrez Gene ID: (Human) 4633, (Rat) 363925, (Mouse) 17906

          View more View less

          Function(s)
          actin monomer binding calcium ion binding protein binding structural constituent of muscle myosin heavy chain binding metal ion binding
          Process(es)
          regulation of the force of heart contraction regulation of striated muscle contraction heart development post-embryonic development muscle filament sliding negative regulation of cell growth muscle cell fate specification muscle fiber development cardiac myofibril assembly ventricular cardiac muscle tissue morphogenesis heart contraction cardiac muscle contraction positive regulation of the force of heart contraction heart morphogenesis
          It has to be done as per old AB suggested Products section.
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