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Invitrogen
Myosin Skeletal Muscle Monoclonal Antibody (MY32)
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Product Details
MA1-90701
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rabbit,
Rat
Published species
Human,
Mouse
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
MY32
Immunogen
Rabbit muscle myosin.
Conjugate
Form
Liquid
Concentration
Conc. Not Determined
Storage buffer
ascites
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_1955676
Product Specific Information
This antibody recognizes heavy chain human skeletal myosin (fast-twitch type II isomyosin). It does not stain cardiac or smooth muscle myosin.
For antigen retrieval, it is recommended to use a citrate buffer, pH 6.0, at room temperature for 30 min.
Store as a concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.
Target Information
Myosin is a major contractile protein which converts chemical energy into mechanical energy through the hydrolysis of ATP. Myosin is a hexameric protein composed of a pair of myosin heavy chains (MYH) and two pairs of nonidentical light chains. Myosin heavy chains are encoded by a multigene family. In mammals at least 10 different myosin heavy chain (MYH) isoforms have been described from striated, smooth, and nonmuscle cells. These isoforms show expression that is spatially and temporally regulated during development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 2A myosin heavy chain; 2B myosin heavy chain; epididymis luminal protein 71; fast 2a myosin heavy chain; inclusion body myopathy 3, autosomal dominant; MGC133384; myh4; MyHC-2a; MyHC-2b; MyHC-2x; MyHC-IIa; MyHC-IIb; MyHC-IIx/d; Myosin heavy chain 1; Myosin heavy chain 2; Myosin heavy chain 2a; Myosin heavy chain 2b; Myosin heavy chain 2x; Myosin heavy chain 4; Myosin heavy chain IIa; Myosin heavy chain IIb; Myosin heavy chain IIx/d; myosin heavy chain isoform 2b; myosin heavy chain type IIb; myosin heavy chain type IIx; Myosin heavy chain, skeletal muscle; Myosin heavy chain, skeletal muscle, adult 1; Myosin heavy chain, skeletal muscle, adult 2; Myosin heavy chain, skeletal muscle, fetal; Myosin heavy chain, skeletal muscle, juvenile; myosin, heavy chain 1, skeletal muscle, adult; myosin, heavy chain 2, skeletal muscle, adult; myosin, heavy chain 4, skeletal muscle; myosin, heavy polypeptide 1, skeletal muscle, adult; myosin, heavy polypeptide 2, skeletal muscle, adult; myosin, heavy polypeptide 4, skeletal muscle; Myosin-1; Myosin-2; Myosin-4; type 2X myosin heavy chain; type IIA myosin heavy chain
Gene Aliases: HEL71; IBM3; MYH1; MYH2; MYH2A; MYH2B; MYH4; MYHa; MYHas8; MYHC; MyHC-2A; MyHC-2B; MyHC-2x; MyHC-2X/D; MyHC-IIA; MyHC-IIb; MYHSA1; MYHSA2; MYPOP
UniProt ID: (Rabbit) Q28641, (Human) P12882, (Human) Q9UKX2, (Human) Q9Y623, (Rat) Q29RW1
Entrez Gene ID: (Rabbit) 100009548, (Rabbit) 100125991, (Human) 4619, (Human) 4620, (Rabbit) 100009054, (Human) 4622, (Rat) 287408, (Rat) 691644, (Rat) 360543
plasma membrane repair
muscle contraction
metabolic process
response to activity
myosin filament assembly
actin-mediated cell contraction
actin filament-based movement
muscle filament sliding
ATP metabolic process
Fc-gamma receptor signaling pathway involved in phagocytosis
response to gravity
response to muscle activity
response to muscle stretch
muscle structure development
striated muscle contraction
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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