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Invitrogen
Myosin Skeletal/Smooth Muscle Polyclonal Antibody
Product Details
PA1-28038
Product Specifications
Species Reactivity
Bovine,
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Whole myosin (heavy and light chains) from bovine uterus.
Conjugate
Form
Liquid
Concentration
Conc. Not Determined
Storage buffer
whole serum
Contains
15mM sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_1957793
Product Specific Information
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Myosin proteins are motor proteins critical for muscle contraction in both skeletal and smooth muscle. They convert chemical energy from ATP hydrolysis into mechanical energy, generating force and movement along actin filaments. In skeletal muscle, myosin molecules are part of the contractile apparatus, where they form thick filaments that interact with actin thin filaments to produce contraction. Myosin heavy chain (MyHC) isoforms are key determinants of muscle fiber types, contributing to the diversity in muscle function and specialization. Skeletal muscle fibers can express different MyHC isoforms, resulting in fibers with varying speed and endurance characteristics. Smooth muscle myosin, in contrast, is involved in the involuntary contractions of smooth muscle tissues found in the walls of hollow organs, such as the intestines and blood vessels. Smooth muscle myosin's regulatory mechanisms differ significantly from skeletal muscle, involving phosphorylation of the myosin light chain to initiate contraction.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: epididymis luminal protein 71; MyHC-2x; MyHC-IIx/d; Myosin heavy chain 1; Myosin heavy chain 11; Myosin heavy chain 2x; Myosin heavy chain IIx/d; myosin heavy chain SMA; Myosin heavy chain, skeletal muscle, adult 1; Myosin heavy chain, smooth muscle isoform; myosin, heavy chain 1, skeletal muscle, adult; myosin, heavy chain 11, smooth muscle; myosin, heavy polypeptide 1, skeletal muscle, adult; myosin, heavy polypeptide 11, smooth muscle; Myosin-1; Myosin-11; SMMHC; type 2x myosin heavy chain
Gene Aliases: AAT4; BOS_18904; BOS_22758; FAA4; HEL71; KIAA0866; MYH1; MYH11; MYHa; MyHC-2x; MyHC-2X/D; MYHSA1; SMHC; SMMHC
UniProt ID: (Human) P12882, (Bovine) Q9BE40, (Human) P35749
Entrez Gene ID: (Human) 4619, (Bovine) 281337, (Bovine) 530050, (Human) 4629
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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