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Myotilin Antibody (PA5-58081) in IHC
Immunohistochemical staining of Myotilin in human cerebral cortex, lymph node, skeletal muscle and testis using Myotilin Polyclonal Antibody (Product # PA5-58081) (A) shows similar protein distribution across tissues to an independent Myotilin Polyclonal Antibody (B).
Product Details
PA5-58081
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human Myotilin. Recombinant protein control fragment (Product #RP-96838).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2644391
Product Specific Information
Immunogen sequence: MSSSAFPASP QQHAGSNPGQ RVTTTYNQSP ASFLSSILPS QPDYNSSKIP SAMDSNYQQS SAGQPINAKP SQTANAKPIP RTPDHEIQG
Highest antigen sequence identity to the following orthologs: Mouse - 78%, Rat - 79%.
Target Information
This gene encodes a cystoskeletal protein which plays a significant role in the stability of thin filaments during muscle contraction. This protein binds F-actin, crosslinks actin filaments, and prevents latrunculin A-induced filament disassembly. Mutations in this gene have been associated with limb-girdle muscular dystrophy and myofibrillar myopathies. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 57 kDa cytoskeletal protein; Myofibrillar titin-like Ig domains protein; Myotilin; Titin immunoglobulin domain protein; titin immunoglobulin domain protein (myotilin)
Gene Aliases: LGMD1; LGMD1A; MFM3; MYOT; TTID; TTOD
UniProt ID: (Human) Q9UBF9
Entrez Gene ID: (Human) 9499
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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