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Proteintech
Myozenin 2 Polyclonal Antibody
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Product Details
11450-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Myozenin 2 Fusion Protein Ag2008 (1-264 aa encoded by BC017402)
Conjugate
Form
Liquid
Concentration
0.13 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Proteintech's Myozenin-2 antibody 11450-1-AP was raised against full-length protein of human origin and is able to detect a band of approximately 34 kDa in Western blotting.
Immunogen sequence: MLSHNTMMK QRKQQATAIM KEVHGNDVDG MDLGKKVSIP RDIMLEELSH LSNRGARLFK MRQRRSDKYT FENFQYQSRA QINHSIAMQN GKVDGSNLEG GSQQAPLTPP NTPDPRSPPN PDNIAPGYSG PLKEIPPEKF NTTAVPKYYQ SPWEQAISND PELLEALYPK LFKPEGKAEL PDYRSFNRVA TPFGGFEKAS RMVKFKVPDF ELLLLTDPRF MSFVNPLSGR RSFNRTPKGW ISENIPIVIT TEPTDDTTVP ESEDL (1-264 aa encoded by BC017402)
Target Information
The calcineurin-binding protein Myozenin 2, also designated calsarcin-1, is a member of the calsarcin protein family. Calcineurin is a calcium- and calmodulin-dependent protein phosphatase that is involved in controlling the slow fiber gene expression in skeletal muscle and hypertrophy of cardiac muscle. The calsarcins are sarcomeric proteins that couple calcineurin and muscle activity. In cardiac and skeletal muscle cells, Myozenin 2 binds calcineurin to α-actinin at the Z-line of the sarcomere. During embryogenesis, Myozenin 1 and 2 are expressed in developing muscle. The Myozenin 2 gene maps to chromosome 4q and is expressed specifically in adult cardiac and slow-twitch skeletal muscle, while Myozenin 1 is only detected in fast skeletal muscle.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: calcineurin-binding protein calsarcin-1; Calsarcin-1; FATZ-related protein 2; muscle-specific protein; MYOZ2; Myozenin-2; myozenin-like 2
Gene Aliases: 1110012I24Rik; C4orf5; CMH16; CS-1; Fatz-2; MYOZ2; Myozl2
UniProt ID: (Human) Q9NPC6, (Mouse) Q9JJW5
Entrez Gene ID: (Human) 51778, (Mouse) 59006, (Rat) 295426
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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