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.jpg?time=20250104 "N2DL4 Antibody in Immunohistochemistry (Paraffin) (IHC (P))")
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N2DL4 Antibody (MA5-24328) in IHC (P)
Immunohistochemical analysis of ULBP-4/RAET1E was detected in immersion fixed paraffin-embedded sections of human ovarian cancer tissue using mouse Anti-human ULBP-4/RAET1E Monoclonal Antibody (Product # MA5-24328) at 15 µg/mL overnight at 4 °C. Tissue was stained using the Anti-mouse HRP-DAB (brown and counterstained with hematoxylin (blue). Specific staining was localized to plasma membranes of epithelial... View More
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.jpg?time=20250104?time=20250104 "N2DL4 Antibody (MA5-24328) in IHC (P)")
Product Details
MA5-24328
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
709116
Immunogen
Mouse myeloma cell line NS0-derived recombinant human ULBP-4/RAET1E Gly30-Asp225
Conjugate
Form
Lyophilized
Concentration
0.5 mg/mL
Purification
Protein A/G
Storage buffer
PBS with 5% trehalose
Contains
No Preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2606442
Product Specific Information
In Western blots, approximately 20% cross-reactivity with recombinant human (rh) ULBP-2 is observed and no cross-reactivity with rhULBP-1 or rhULBP-3 is observed.
Reconstitute in sterile PBS to a final concentration of 0.5 mg/mL.
Target Information
This gene belong to the RAET1 family, which consists of major histocompatibility complex (MHC) class I-related genes located in a cluster on chromosome 6q24.2-q25.3. This and RAET1G protein differ from other RAET1 proteins in that they have type I membrane-spanning sequences at their C termini rather than glycosylphosphatidylinositol anchor sequences. This protein functions as a ligand for NKG2D receptor, which is expressed on the surface of several types of immune cells, and is involved in innate and adaptive immune responses. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2011].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Lymphocyte effector toxicity activation ligand; MGC125309; N2DL-4; NKG2D ligand 4; RAE-1-like transcript 4; RAE1 like transcript 4; Retinoic acid early transcript 1E; UL16 binding protein 4; UL16-binding protein 4; ULBP 4; ULBP4MGC125308
Gene Aliases: bA350J20.7; LETAL; N2DL-4; N2DL4; NKG2DL4; RAET1E; RAET1E2; RL-4; ULBP4; UNQ1867/PRO4303
UniProt ID: (Human) Q8TD07
Entrez Gene ID: (Human) 135250
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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