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OriGene
NABP1 Monoclonal Antibody (OTI7D9), TrueMAB™
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FIGURE: 1 / 1
NABP1 Antibody (CF811089) in WB
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY NABP1 (RC203672, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-NABP1. Positive lysates LY422167 (100 µg) and LC422167 (20 µg) can be purchased separately from OriGene.
Product Details
CF811089
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
OTI7D9
Immunogen
Full length human recombinant protein of human NABP1 produced in E.coli.
Conjugate
Form
Lyophilized
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 8% trehalose
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
Target Information
NABP1, also known as NABP1/Ssb2, is a single-stranded DNA-binding protein involved in genome maintenance and stability. The gene encoding NABP1 is regulated by RORgamma2, a retinoid-related orphan receptor critical for thymopoiesis. Research has demonstrated that NABP1 plays a compensatory role in thymic maturation, particularly in conditions where its homolog, SSB1, is knocked out. Despite SSB1’s vital role in neonatal survival, NABP1 remains non-essential for thymic maturation and male fertility, indicating partial functional redundancy between these proteins. Furthermore, studies on the C-terminal regions of NABP1 have shown distinct roles in nucleic acid binding, contributing to DNA and RNA metabolism. These findings highlight NABP1’s importance in genomic integrity and its complex interplay within cellular processes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: hSSB2; Nucleic acid-binding protein 1; oligonucleotide/oligosaccharide-binding fold containing 2A; Oligonucleotide/oligosaccharide-binding fold-containing protein 2A; Sensor of single-strand DNA complex subunit B2; Sensor of ssDNA subunit B2; Single-stranded DNA-binding protein 2; SOSS complex subunit B2; SOSS-B2
Gene Aliases: NABP1; OBFC2A; SOSS-B2; SSB2
UniProt ID: (Human) Q96AH0
Entrez Gene ID: (Human) 64859
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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