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Immunogen sequence: SSCISLPPVL SDGDDDLQVE KENKNFPLKT KDELLLNELP SVEELTIILP EDIELKPLGM VSSIIEQLVI IESMTNLPPV NEETVIFKSD RQAAGKIF
Highest antigen sequence identity to the following orthologs: Mouse - 89%, Rat - 90%.
RNA-binding protein required for the maturation of box H/ACA snoRNPs complex and ribosome biogenesis. During assembly of the H/ACA snoRNPs complex, it associates with the complex and disappears during maturation of the complex and is replaced by NOLA1/GAR1 to yield mature H/ACA snoRNPs complex. Probably competes with NOLA1/GAR1 for binding with DKC1/NOLA4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: H/ACA ribonucleoprotein complex non-core subunit NAF1; hNAF1; nuclear assembly factor 1 homolog
Gene Aliases: NAF1
UniProt ID: (Human) Q96HR8
Entrez Gene ID: (Human) 92345
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