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Proteintech
NAGS Polyclonal Antibody
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Product Details
21566-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
NAGS Fusion Protein Ag16073 (167-534 aa encoded by BC111713)
Conjugate
Form
Liquid
Concentration
0.13 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MDMKPLVVL GLPAPTAPSG CLSFWEAKAQ LAKSCKVLVD ALRHNAAAAV PFFGGGSVLR AAEPAPHASY GGIVSVETDL LQWCLESGSI PILCPIGETA ARRSVLLDSL EVTASLAKAL RPTKIIFLNN TGGLRDSSHK VLSNVNLPAD LDLVCNAEWV STKERQQMRL IVDVLSRLPH HSSAVITAAS TLLTELFSNK GSGTLFKNAE RMLRVRSLDK LDQGRLVDLV NASFGKKLRD DYLASLRPRL HSIYVSEGYN AAAILTMEPV LGGTPYLDKF VVSSSRQGQG SGQMLWECLR RDLQTLFWRS RVTNPINPWY FKHSDGSFSN KQWIFFWFGL ADIRDSYELV NHAKGLPDSF HKPASDPGS (167-534 aa encoded by BC111713)
Target Information
NAGS is a mitochondrial enzyme that catalyzes the formation of N-acetylglutamate (NAG) from glutamate and acetyl coenzyme-A. NAG is a cofactor of carbamyl phosphate synthetase I (CPSI), the first enzyme of the urea cycle in mammals. Deficiencies in N-acetylglutamate synthase have been associated with hyperammonemia.The N-acetylglutamate synthase gene encodes a mitochondrial enzyme that catalyzes the formation of N-acetylglutamate (NAG) from glutamate and acetyl coenzyme-A. NAG is a cofactor of carbamyl phosphate synthetase I (CPSI), the first enzyme of the urea cycle in mammals. This gene may regulate ureagenesis by altering NAG availability and, thereby, CPSI activity. Deficiencies in N-acetylglutamate synthase have been associated with hyperammonemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Amino-acid acetyltransferase; amino-acid N-acetyltransferase; MGC133025; N-acetylglutamate synthase, mitochondrial
Gene Aliases: 1700120E20Rik; AGAS; ARGA; NAGS; RGD1565783
UniProt ID: (Human) Q8N159, (Mouse) Q8R4H7
Entrez Gene ID: (Human) 162417, (Rat) 303563, (Mouse) 217214
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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