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A suggested positive control is K562 cell lysate.
PA5-21028 can be used with blocking peptide PEP-1142.
NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP13 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. While little is known about the function of NALP13, it has been suggested that it may be implicated in the activation of proinflammatory caspases via inflammasomes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: NACHT, leucine rich repeat and PYD containing 13; NACHT, LRR and PYD containing protein 13; NACHT, LRR and PYD domains-containing protein 13; NLR family, pyrin domain containing 13; Nucleotide-binding oligomerization domain protein 14; nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 13
Gene Aliases: CLR19.7; NALP13; NLRP13; NOD14; PAN13
UniProt ID: (Human) Q86W25
Entrez Gene ID: (Human) 126204
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