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Proteintech
NAMPT/PBEF Monoclonal Antibody (3D4D8)
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Product Details
66385-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
3D4D8
Immunogen
NAMPT/PBEF Fusion Protein Ag2434 (1-350 aa encoded by BC020691)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MNPAAEAEF NILLATDSYK VTHYKQYPPN TSKVYSYFEC REKKTENSKL RKVKYEETVF YGLQYILNKY LKGKVVTKEK IQEAKDVYKE HFQDDVFNEK GWNYILEKYD GHLPIEIKAV PEGFVIPRGN VLFTVENTDP ECYWLTNWIE TILVQSWYPI TVATNSREQK KILAKYLLET SGNLDGLEYK LHDFGYRGVS SQETAGIGAS AHLVNFKGTD TVAGLALIKK YYGTKDPVPG YSVPAAEHST ITAWGKDHEK DAFEHIVTQF SSVPVSVVSD SYDIYNACEK IWGEDLRHLI VSRSTQAPLI IRPDSGNPLD TVLKVLEILG KKFPVTENSK GYKLLPPYLR V (1-350 aa encoded by BC020691)
Target Information
Visfatin, also known as pre-B cell colony-enhancing factor, is an adipocytokine that is abundantly secreted by visceral adipose tissue, with insulin mimetic effects. Visfatin mimics insulin signaling by binding to the insulin receptor and reducing glucose release from liver cells, while stimulating glucose utilization in adipocytes and myocytes. Visfatin is also invoved in enhancement of cell proliferation, biosynthesis of nicotinamide mono-and dinucleotide and glucose homeostasis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: DKFZp666B131; EC 2.4.2.12; MGC117256; NAmPRTase; Nicotinamide phosphoribosyltransferase; PBEF; Pre-B cell-enhancing factor; pre-B-cell colony enhancing factor 1; Pre-B-cell colony-enhancing factor 1; Pre-B-cell colony-enhancing factor 1 homolog; Visfatin
Gene Aliases: 1110035O14Rik; AI314458; AI480535; NAmPRTase; NAMPT; PBEF; PBEF1; VF; VISFATIN
UniProt ID: (Human) P43490, (Mouse) Q99KQ4, (Rat) Q80Z29
Entrez Gene ID: (Human) 10135, (Mouse) 59027, (Rat) 297508
NAD biosynthetic process
pyridine nucleotide biosynthetic process
circadian regulation of gene expression
positive regulation of transcription from RNA polymerase II promoter
rhythmic process
positive regulation of smooth muscle cell proliferation
positive regulation of nitric-oxide synthase biosynthetic process
nicotinamide metabolic process
signal transduction
cell-cell signaling
female pregnancy
circadian rhythm
positive regulation of cell proliferation
insulin receptor signaling pathway
response to organic cyclic compound
adipose tissue development
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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