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Bethyl Laboratories
NAMPT/PBEF/Visfatin Recombinant Rabbit Monoclonal Antibody (BLR058F)
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NAMPT/PBEF/Visfatin Antibody (A700-058) in ICC/IF
Detection of human NAMPT/PBEF/Visfatin by immunocytochemistry. Sample: FFPE section of NCI-H460. Antibody: Rabbit anti-NAMPT/PBEF/Visfatin recombinant monoclonal antibody [BLR058F] (Product # A700-058) (lot 1) used at 1:250. Secondary: HRP-conjugated goat anti-rabbit IgG (A120-501P). Substrate: DAB.
Product Details
A700-058
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
BLR058F
Immunogen
Peptide representing a region between residue 400 and 450 of human Nicotinamide phosphoribosyltransferase precursor (NAMPT).
Conjugate
Form
Liquid
Concentration
250 µg/mL
Purification
purified
Storage buffer
BBS, pH 7.8 to 8.6, with 0.1% BSA
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Visfatin, also known as pre-B cell colony-enhancing factor, is an adipocytokine that is abundantly secreted by visceral adipose tissue, with insulin mimetic effects. Visfatin mimics insulin signaling by binding to the insulin receptor and reducing glucose release from liver cells, while stimulating glucose utilization in adipocytes and myocytes. Visfatin is also invoved in enhancement of cell proliferation, biosynthesis of nicotinamide mono-and dinucleotide and glucose homeostasis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DKFZp666B131; EC 2.4.2.12; MGC117256; NAmPRTase; Nicotinamide phosphoribosyltransferase; PBEF; Pre-B cell-enhancing factor; pre-B-cell colony enhancing factor 1; Pre-B-cell colony-enhancing factor 1; Pre-B-cell colony-enhancing factor 1 homolog; Visfatin
Gene Aliases: 1110035O14Rik; AI314458; AI480535; NAmPRTase; NAMPT; PBEF; PBEF1; VF; VISFATIN
UniProt ID: (Human) P43490, (Mouse) Q99KQ4
Entrez Gene ID: (Human) 10135, (Mouse) 59027
NAD biosynthetic process
pyridine nucleotide biosynthetic process
circadian regulation of gene expression
positive regulation of transcription from RNA polymerase II promoter
rhythmic process
positive regulation of smooth muscle cell proliferation
positive regulation of nitric-oxide synthase biosynthetic process
nicotinamide metabolic process
signal transduction
cell-cell signaling
female pregnancy
circadian rhythm
positive regulation of cell proliferation
insulin receptor signaling pathway
response to organic cyclic compound
adipose tissue development
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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