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Product Details
15163-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
NANS Fusion Protein Ag7271 (1-359 aa encoded by BC000008)
Conjugate
Form
Liquid
Concentration
0.13 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MPLELELCP GRWVGGQHPC FIIAEIGQNH QGDLDVAKRM IRMAKECGAD CAKFQKSELE FKFNRKALER PYTSKHSWGK TYGEHKRHLE FSHDQYRELQ RYAEEVGIFF TASGMDEMAV EFLHELNVPF FKVGSGDTNN FPYLEKTAKK GRPMVISSGM QSMDTMKQVY QIVKPLNPNF CFLQCTSAYP LQPEDVNLRV ISEYQKLFPD IPIGYSGHET GIAISVAAVA LGAKVLERHI TLDKTWKGSD HSASLEPGEL AELVRSVRLV ERALGSPTKQ LLPCEMACNE KLGKSVVAKV KIPEGTILTM DMLTVKVGEP KGYPPEDIFN LVGKKVLVTV EEDDTIMEEL VDNHGKKIKS (1-359 aa encoded by BC000008)
Target Information
This gene encodes an enzyme that functions in the biosynthetic pathways of sialic acids. In vitro, the encoded protein uses N-acetylmannosamine 6-phosphate and mannose 6-phosphate as substrates to generate phosphorylated forms of N-acetylneuraminic acid (Neu5Ac) and 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN), respectively; however, it exhibits much higher activity toward the Neu5Ac phosphate product. In insect cells, expression of this gene results in Neu5Ac and KDN production. This gene is related to the E. coli sialic acid synthase gene neuB, and it can partially restore sialic acid synthase activity in an E. coli neuB-negative mutant.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 3-deoxy-D-glycero-D-galacto-nononate 9-phosphate synthase; epididymis secretory protein Li 100; N-acetylneuraminate-9-phosphate synthase; N-acetylneuraminic acid 9-phosphate synthetase; N-acetylneuraminic acid phosphate synthase; N-acetylneuraminic acid synthase; NANS; RP11-404F11.3; Sialic acid phosphate synthase; Sialic acid synthase
Gene Aliases: 4632418E04Rik; BB056474; HEL-S-100; NANS; SAS; SEMDG
UniProt ID: (Human) Q9NR45, (Mouse) Q99J77
Entrez Gene ID: (Human) 54187, (Mouse) 94181, (Rat) 298071
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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