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Bethyl Laboratories
NCBP2 Polyclonal Antibody
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Product Details
A302-552A
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residue 1 and 50 of human nuclear cap binding protein subunit 2.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
tris citrate/phosphate, pH 7-8
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
Based on 100% sequence identity, this antibody is predicted to react with Mouse, Rat and Bovine
Target Information
The product of this gene is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' cap of nascent pre-mRNA in the nucleoplasm. The encoded protein has an RNP domain commonly found in RNA binding proteins, and contains the cap-binding activity. The CBC promotes pre-mRNA splicing, 3'-end processing, RNA nuclear export, and nonsense-mediated mRNA decay. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 20 kDa nuclear cap-binding protein; CBP20; Cell proliferation-inducing gene 55 protein; NCBP 20 kDa subunit; NCBP interacting protein 1; NCBP-interacting protein 1; NIP1; nuclear cap binding protein subunit 2, 20kD; nuclear cap binding protein subunit 2, 20kDa; Nuclear cap-binding protein subunit 2
Gene Aliases: CBC2; CBP20; NCBP2; NIP1; PIG55
UniProt ID: (Human) P52298
Entrez Gene ID: (Human) 22916
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
mRNA splicing, via spliceosome
transcription from RNA polymerase II promoter
transcription elongation from RNA polymerase II promoter
termination of RNA polymerase II transcription
7-methylguanosine mRNA capping
RNA export from nucleus
mRNA export from nucleus
snRNA export from nucleus
regulation of translational initiation
histone mRNA metabolic process
RNA splicing
fibroblast growth factor receptor signaling pathway
gene expression
gene silencing by RNA
mRNA 3'-end processing
positive regulation of mRNA 3'-end processing
snRNA transcription from RNA polymerase II promoter
mRNA cis splicing, via spliceosome
positive regulation of RNA export from nucleus
nuclear export
pre-mRNA cleavage required for polyadenylation
regulation of mRNA polyadenylation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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