Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
NCBP2 Polyclonal Antibody
Promotion
View available promotion(s)
Promo code: {{promo.promoCode}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
FIGURE: 1 / 4
NCBP2 Antibody (PA5-75234) in IHC (P)
Immunohistochemistry analysis of NCBP2 in paraffin-embedded human breast carcinoma tissue (cytoplasmic and nucleus staining) and negative control (right, with PBS only). Samples were incubated with NCBP2 polyclonal antibody (Product # PA5-75234) at a dilution of 1:50, followed by goat Anti-Rabbit IgG-biotin and avidin peroxidase.
Product Details
PA5-75234
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to amino acids N-terminus of Human NCBP2.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2718962
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Target Information
The product of this gene is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' cap of nascent pre-mRNA in the nucleoplasm. The encoded protein has an RNP domain commonly found in RNA binding proteins, and contains the cap-binding activity. The CBC promotes pre-mRNA splicing, 3'-end processing, RNA nuclear export, and nonsense-mediated mRNA decay. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: 20 kDa nuclear cap-binding protein; CBP20; Cell proliferation-inducing gene 55 protein; NCBP 20 kDa subunit; NCBP interacting protein 1; NCBP-interacting protein 1; NIP1; nuclear cap binding protein subunit 2, 20kD; nuclear cap binding protein subunit 2, 20kDa; Nuclear cap-binding protein subunit 2
Gene Aliases: 20kDa; 5930413E18Rik; AA536802; AI843301; C79367; CBC2; CBP20; NCBP2; NIP1; PIG55
UniProt ID: (Human) P52298, (Mouse) Q9CQ49, (Rat) B1WC40
Entrez Gene ID: (Human) 22916, (Mouse) 68092, (Rat) 689116
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
mRNA splicing, via spliceosome
7-methylguanosine mRNA capping
mRNA processing
regulation of translation
regulation of translational initiation
transport
RNA splicing
gene silencing by RNA
mRNA cis splicing, via spliceosome
mRNA transport
transcription from RNA polymerase II promoter
transcription elongation from RNA polymerase II promoter
termination of RNA polymerase II transcription
RNA export from nucleus
mRNA export from nucleus
snRNA export from nucleus
histone mRNA metabolic process
fibroblast growth factor receptor signaling pathway
gene expression
mRNA 3'-end processing
positive regulation of mRNA 3'-end processing
snRNA transcription from RNA polymerase II promoter
positive regulation of RNA export from nucleus
nuclear export
pre-mRNA cleavage required for polyadenylation
regulation of mRNA polyadenylation
biological_process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support