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Invitrogen
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Immunogen sequence: AYNMVPPKVK CLTKIWHPNI TETGEICLSL LREHSIDGTG WAPTRTLKDV VWGLNSLFTD LLNFDDPLNI EAAEHHLRDK EDFRNKVDDY
Accepts the ubiquitin-like protein NEDD8 from the UBA3-NAE1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E3 ubiquitin ligase RBX2, but not RBX1, suggests that the RBX2-UBE2F complex neddylates specific target proteins, such as CUL5.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: MGC18120; NEDD8 carrier protein UBE2F; NEDD8 protein ligase UBE2F; NEDD8-conjugating enzyme 2; NEDD8-conjugating enzyme UBE2F; RING-type E3 NEDD8 transferase UBE2F; ubiquitin conjugating enzyme E2F (putative); Ubiquitin-conjugating enzyme E2 F; ubiquitin-conjugating enzyme E2F (putative)
Gene Aliases: NCE2; UBE2F
UniProt ID: (Human) Q969M7
Entrez Gene ID: (Human) 140739
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