Proteintech

NCKAP1 Polyclonal Antibody

NCKAP1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

FIGURE: 1 / 7

NCKAP1 Antibody (12140-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded human gliomas tissue slide using 12140-1-AP ( NAP1;NCKAP1 Antibody) at dilution of 1:50 (under 40x lens).

Product Image Gallery

Product Details

12140-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

View 6 publications 6 publications

Immunohistochemistry (IHC)

View 2 publications 2 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Miscellaneous PubMed (MISC)

View 1 publication 1 publication

Not applicable (N/A)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

NCKAP1 Fusion Protein Ag2788 (779-1129 aa encoded by BC015025)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.13 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: HGEPTITSL YTNWYLETLL RQVSNGHIAY FPAMKAFVNL PTENELTFNA EEYSDISEMR SLSELLGPYG MKFLSESLMW HISSQVAELK KLVVENVDVL TQMRTSFDKP DQMAALFKRL SSVDSVLKRM TIIGVILSFR SLAQEALRDV LSYHIPFLVS SIEDFKDHIP RETDMKVAMN VYELSSAAGL PCEIDPALVV ALSSQKSENI SPEEEYKIAC LLMVFVAVSL PTLASNVMSQ YSPAIEGHCN NIHCLAKAIN QIAAALFTIH KGSIEDRLKE FLALASSSLL KIGQETDKTT TRNRESVYLL LDMIVQESPF LTMDLLESCF PYVLLRNAYH AVYKQSVTSS A (779-1129 aa encoded by BC015025)

Target Information

This gene interacts with Nck and may be involved in the downstream signaling of Nck and shares similarity with the mouse Dhm1 and the yeast dhp1 gene. The yeast gene is involved in homologous recombination and RNA metabolism, such as RNA synthesis and RNA trafficking. Complementation studies show that Dhm1 has a similar function in mouse as dhp1. The function of the human gene has not yet been determined. Transcript variants encoding different isoforms have been noted for this gene; however, their full-length nature is not known.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

NCKAP1 is a Prognostic Biomarker for Inhibition of Cell Growth in Clear Cell Renal Cell Carcinoma.

Frontiers in genetics

Chen J,Ge J,Zhang W,Xie X,Zhong X,Tang S

Sat Aug 13 00:00:00 UTC 2022

NCKAP1 is a Prognostic Biomarker for Inhibition of Cell Growth in Clear Cell Renal Cell Carcinoma.

Frontiers in genetics

Chen J,Ge J,Zhang W,Xie X,Zhong X,Tang S

Sat Aug 13 00:00:00 UTC 2022

NCKAP1 is a Prognostic Biomarker for Inhibition of Cell Growth in Clear Cell Renal Cell Carcinoma.

Frontiers in genetics

Chen J,Ge J,Zhang W,Xie X,Zhong X,Tang S

Sat Aug 13 00:00:00 UTC 2022

NCKAP1 is a Prognostic Biomarker for Inhibition of Cell Growth in Clear Cell Renal Cell Carcinoma.

Frontiers in genetics

Chen J,Ge J,Zhang W,Xie X,Zhong X,Tang S

Sat Aug 13 00:00:00 UTC 2022

Parallel kinase pathways stimulate actin polymerization at depolarized mitochondria.

Current biology : CB

Fung TS,Chakrabarti R,Kollasser J,Rottner K,Stradal TEB,Kage F,Higgs HN

Mon Apr 11 00:00:00 UTC 2022

Abelson interactor 1 splice isoform-L plays an anti-oncogenic role in colorectal carcinoma through interactions with WAVE2 and full-length Abelson interactor 1.

World journal of gastroenterology

Li K,Peng YF,Guo JZ,Li M,Zhang Y,Chen JY,Lin TR,Yu X,Yu WD

Wed Apr 21 00:00:00 UTC 2021

NCKAP1 improves patient outcome and inhibits cell growth by enhancing Rb1/p53 activation in hepatocellular carcinoma.

Cell death & disease

Zhong XP,Kan A,Ling YH,Lu LH,Mei J,Wei W,Li SH,Guo RP

Wed May 08 00:00:00 UTC 2019

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Gromnitza S,Lepa C,Weide T,Schwab A,Pavenstädt H,George B

Thu Mar 01 00:00:00 UTC 2018

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.

Scientific reports

Wilkinson B,Li J,Coba MP

Thu Jul 13 00:00:00 UTC 2017

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.

Scientific reports

Wilkinson B,Li J,Coba MP

Thu Jul 13 00:00:00 UTC 2017

Selenoprotein S is involved in maintenance and transport of multiprotein complexes.

The Biochemical journal

Turanov AA,Shchedrina VA,Everley RA,Lobanov AV,Yim SH,Marino SM,Gygi SP,Hatfield DL,Gladyshev VN

Mon Sep 15 00:00:00 UTC 2014

Selenoprotein S is involved in maintenance and transport of multiprotein complexes.

The Biochemical journal

Turanov AA,Shchedrina VA,Everley RA,Lobanov AV,Yim SH,Marino SM,Gygi SP,Hatfield DL,Gladyshev VN

Mon Sep 15 00:00:00 UTC 2014

Nudel is crucial for the WAVE complex assembly in vivo by selectively promoting subcomplex stability and formation through direct interactions.

Cell research

Wu S,Ma L,Wu Y,Zeng R,Zhu X

Wed Aug 01 00:00:00 UTC 2012

Nudel is crucial for the WAVE complex assembly in vivo by selectively promoting subcomplex stability and formation through direct interactions.

Cell research

Wu S,Ma L,Wu Y,Zeng R,Zhu X

Wed Aug 01 00:00:00 UTC 2012

Bioinformatics

Protein Aliases: Brain protein H19; Membrane-associated protein HEM-2; MH19; NAP 1; Nck-associated protein 1; p125Nap1

View more View less

Gene Aliases: C79304; H19; Hem-2; HEM2; KIAA0587; mh19; mKIAA0587; NAP1; NAP125; NCKAP1; p125Nap1

View more View less

UniProt ID: (Human) Q9Y2A7, (Mouse) P28660, (Rat) P55161

View more View less

Entrez Gene ID: (Human) 10787, (Mouse) 50884, (Rat) 58823

View more View less

Function(s)

protein binding protein complex binding Rac GTPase binding

Process(es)

in utero embryonic development somitogenesis neural tube closure zygotic determination of anterior/posterior axis, embryo endoderm development mesodermal cell migration embryonic body morphogenesis positive regulation of lamellipodium assembly Rac protein signal transduction lamellipodium assembly notochord development establishment or maintenance of actin cytoskeleton polarity regulation of protein localization embryonic heart tube development cell migration involved in gastrulation basal protein localization apical protein localization paraxial mesoderm development paraxial mesoderm morphogenesis notochord morphogenesis embryonic foregut morphogenesis protein stabilization positive regulation of Arp2/3 complex-mediated actin nucleation apoptotic process central nervous system development viral process Fc-gamma receptor signaling pathway involved in phagocytosis vascular endothelial growth factor receptor signaling pathway

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more

NCKAP1 Polyclonal Antibody

NCKAP1 Antibody (12140-1-AP) in IHC (P)

Product Details

12140-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Miscellaneous PubMed (MISC)

Not applicable (N/A)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

We're here to help

Your items have has been added!