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Proteintech
NCOA1/SRC-1 Polyclonal Antibody
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Product Details
21952-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein
Conjugate
Form
Liquid
Purification
Antigen affinity chromatography
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: RQRQLIQQQR AMLMRQQSFG NNLPPSSGLP VQMGNPRLPQ GAPQQFPYPP NYGTNPGTPP ASTSPFSQLA ANPEASLANR NSMVSRGMTG NIGGQFGTGI NPQMQQNVFQ YPGAGMVPQG EANFAPSLSP GSSMVPMPIP PPQSSLLQQT PPASGYQSPD MKAWQQGAIG NNNVFSQAVQ NQPTPAQPGV YNNMSITVSM AGGNTNVQNM NPMMAQMQMS SLQMPGMNTV CPEQINDPAL RHTGLYCNQL SSTDLLKTEA DGTQQVQQVQ VFADVQCTVN LVGGDPYLNQ PGPLGTQKPT SGPQTPQAQQ KSLLQQLLTE
Target Information
Clone 1135 recognizes SRC-1, steroid-receptor coactivator-1. SRC-1 is a member of a gene family that functions in the full transcriptional activation of the steroid hormone receptor superfamily and contains intrinsic histone acetyltransferase activity. SRC-1 has a molecular weight of 160 kDa and has a basic helix-loop-helix (bHLH)-PAS domain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ASV; bHLHe74; c-SRC; Class E basic helix-loop-helix protein 74; Hin-2 protein; NCoA-1; Nuclear receptor coactivator 1; p60-Src; PAX3/NCOA1 fusion protein; Protein Hin-2; Renal carcinoma antigen NY-REN-52; RIP160; SRC-1; SRC-1 (-Q); Steroid receptor coactivator 1; steroid receptor coactivator-1
Gene Aliases: bHLHe42; BHLHE74; F-SRC-1; KAT13A; NCOA1; RIP160; SRC1
UniProt ID: (Human) Q15788
Entrez Gene ID: (Human) 8648
RNA polymerase II regulatory region DNA binding
RNA polymerase II transcription coactivator activity
chromatin binding
transcription coactivator activity
histone acetyltransferase activity
protein binding
ligand-dependent nuclear receptor binding
enzyme binding
estrogen receptor binding
ligand-dependent nuclear receptor transcription coactivator activity
protein complex binding
progesterone receptor binding
nuclear hormone receptor binding
retinoid X receptor binding
protein dimerization activity
protein N-terminus binding
androgen receptor binding
positive regulation of transcription from RNA polymerase II promoter by galactose
regulation of thyroid hormone mediated signaling pathway
transcription, DNA-templated
lactation
male gonad development
bile acid and bile salt transport
cerebellum development
hippocampus development
hypothalamus development
cerebral cortex development
androgen receptor signaling pathway
intracellular receptor signaling pathway
response to estradiol
response to retinoic acid
response to progesterone
cellular response to hormone stimulus
positive regulation of apoptotic process
histone H4 acetylation
cellular lipid metabolic process
estrous cycle
positive regulation of neuron differentiation
positive regulation of transcription, DNA-templated
positive regulation of female receptivity
positive regulation of transcription from RNA polymerase II promoter
male mating behavior
labyrinthine layer morphogenesis
cellular response to Thyroglobulin triiodothyronine
regulation of cellular response to drug
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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