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Product Details
PA5-142707
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Peptide with sequence KEAELAARILLDQGQ-C (aa 25-39).
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Ammonium sulfate precipitation
Storage buffer
TBS, pH 7.3, with 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2933353
Product Specific Information
Additional Information: This antibody is expected to recognize reported isoform a (NP_963293.1) only.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:16,000.
Target Information
NDRG2's gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. NDRG2 is a cytoplasmic protein that may play a role in neurite outgrowth. Its gene may be involved in glioblastoma carcinogenesis.This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein that may play a role in neurite outgrowth. This gene may be involved in glioblastoma carcinogenesis. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Antidepressant-related protein ADRG123; cytoplasmic protein Ndr1; DKFZp781G1938; FLJ25522; N-myc downstream regulated 2; N-myc downstream regulated gene 2; N-myc downstream regulator 2; N-myc downstream-regulated gene 2 protein; NDR1-related protein NDR2; NDRG1-related protein; NDRG2var; Protein Ndr2; Protein NDRG2; Protein Syld709613; syld709613 protein
Gene Aliases: AI182517; AU040374; KIAA1248; Ndr2; NDRG2; SYLD
UniProt ID: (Human) Q9UN36, (Mouse) Q9QYG0, (Rat) Q8VBU2
Entrez Gene ID: (Human) 57447, (Mouse) 29811, (Rat) 171114
negative regulation of cytokine production
signal transduction
multicellular organism development
nervous system development
regulation of vascular endothelial growth factor production
Wnt signaling pathway
cell differentiation
negative regulation of smooth muscle cell proliferation
negative regulation of ERK1 and ERK2 cascade
regulation of platelet-derived growth factor production
substantia nigra development
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