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Product Details
H00065009-M01
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
2G3
Immunogen
NDRG4 (AAH11795.1, 1 a.a. approximately 339 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
0.4 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Cell lysate).
Immunogen sequence: MPECWDGEHD IETPYGLLHV VIRGSPKGNR PAILTYHDVG LNHKLCFNTF FNFEDMQEIT KHFVVCHVDA PGQQVGASQF PQGYQFPSME QLAAMLPSVV QHFGFKYVIG IGVGAGAYVL AKFALIFPDL VEGLVLVNID PNGKGWIDWA ATKLSGLTST LPDTVLSHLF SQEELVNNTE LVQSYRQQIG NVVNQANLQL FWNMYNSRRD LDINRPGTVP NAKTLRCPVM LVVGDNAPAE DGVVECNSKL DPTTTTFLKM ADSGGLPQVT QPGKLTEAFK YFLQGMGYMP SASMTRLARS RTASLTSASS VDGSRPQACT HSESSEGLGQ VNHTMEVSC
Target Information
This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein that may be involved in the regulation of mitogenic signaling in vascular smooth muscles cells. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Brain development-related molecule 1; DKFZp686I1615; FLJ30586; FLJ42011; MGC19632; N-myc downstream regulated 1, related sequence; N-myc downstream-regulated gene 4 protein; Protein Ndr4; Protein NDRG4; SMAP-8; smooth muscle-associated protein 8; Vascular smooth muscle cell-associated protein 8
Gene Aliases: BDM1; D8Bwg1337e; KIAA1180; Ndr1-rs; Ndr4; NDRG4; R74996; SMAP-8; SMAP8
UniProt ID: (Human) Q9ULP0, (Mouse) Q8BTG7
Entrez Gene ID: (Human) 65009, (Mouse) 234593
signal transduction
brain development
visual learning
negative regulation of platelet-derived growth factor receptor signaling pathway
positive regulation of neuron projection development
negative regulation of smooth muscle cell migration
vesicle docking
negative regulation of smooth muscle cell proliferation
cell migration involved in heart development
positive regulation of ERK1 and ERK2 cascade
regulation of endocytic recycling
heart looping
response to stress
cell growth
cell differentiation
embryonic heart tube development
cardiac muscle cell proliferation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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