Proteintech

NDST1 Polyclonal Antibody

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NDST1 Antibody (26203-1-AP) in WB

Various lysates were subjected to SDS PAGE followed by western blot with (Product # 26203-1-AP) NDST1 antibody at dilution of 1:1,000 incubated at room temperature for 1.5 hours.

NDST1 Antibody in Immunoprecipitation (IP)

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Product Details

26203-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 6 publications 6 publications

Immunocytochemistry (ICC/IF)

View 1 publication 1 publication

Flow Cytometry (Flow)

View 1 publication 1 publication

Immunoprecipitation (IP)

0.5-4.0 µg

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

NDST1 Fusion Protein Ag24422 (38-90 aa encoded by BC012888)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.27 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: LYGWKRGLE PSADAPEPDC GDPPPVAPSR LLPLKPVQAA TPSRTDPLVL VFVE (38-90 aa encoded by BC012888)

Target Information

Essential bifunctional enzyme that catalyzes both the N- deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA disaccharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Plays a role in determining the extent and pattern of sulfation of heparan sulfate. Compared to other NDST enzymes, its presence is absolutely required. Participates in biosynthesis of heparan sulfate that can ultimately serve as L- selectin ligands, thereby playing a role in inflammatory response.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Macrophage lineage cells-derived migrasomes activate complement-dependent blood-brain barrier damage in cerebral amyloid angiopathy mouse model.

Nature communications

Hu M,Li T,Ma X,Liu S,Li C,Huang Z,Lin Y,Wu R,Wang S,Lu D,Lu T,Men X,Shen S,Huang H,Liu Y,Song K,Jian B,Jiang Y,Qiu W,Liu Q,Lu Z,Cai W

Tue Jul 04 00:00:00 UTC 2023

Macrophage lineage cells-derived migrasomes activate complement-dependent blood-brain barrier damage in cerebral amyloid angiopathy mouse model.

Nature communications

Hu M,Li T,Ma X,Liu S,Li C,Huang Z,Lin Y,Wu R,Wang S,Lu D,Lu T,Men X,Shen S,Huang H,Liu Y,Song K,Jian B,Jiang Y,Qiu W,Liu Q,Lu Z,Cai W

Tue Jul 04 00:00:00 UTC 2023

Macrophage lineage cells-derived migrasomes activate complement-dependent blood-brain barrier damage in cerebral amyloid angiopathy mouse model.

Nature communications

Hu M,Li T,Ma X,Liu S,Li C,Huang Z,Lin Y,Wu R,Wang S,Lu D,Lu T,Men X,Shen S,Huang H,Liu Y,Song K,Jian B,Jiang Y,Qiu W,Liu Q,Lu Z,Cai W

Tue Jul 04 00:00:00 UTC 2023

Macrophage lineage cells-derived migrasomes activate complement-dependent blood-brain barrier damage in cerebral amyloid angiopathy mouse model.

Nature communications

Hu M,Li T,Ma X,Liu S,Li C,Huang Z,Lin Y,Wu R,Wang S,Lu D,Lu T,Men X,Shen S,Huang H,Liu Y,Song K,Jian B,Jiang Y,Qiu W,Liu Q,Lu Z,Cai W

Tue Jul 04 00:00:00 UTC 2023

Bone Marrow Mesenchymal Stem Cell-Derived Dermcidin-Containing Migrasomes enhance LC3-Associated Phagocytosis of Pulmonary Macrophages and Protect against Post-Stroke Pneumonia.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Li T,Su X,Lu P,Kang X,Hu M,Li C,Wang S,Lu D,Shen S,Huang H,Liu Y,Deng X,Cai W,Wei L,Lu Z

Tue Aug 01 00:00:00 UTC 2023

TSPAN4-positive migrasome derived from retinal pigmented epithelium cells contributes to the development of proliferative vitreoretinopathy.

Journal of nanobiotechnology

Wu L,Yang S,Li H,Zhang Y,Feng L,Zhang C,Wei J,Gu X,Xu G,Wang Z,Wang F

Fri Dec 09 00:00:00 UTC 2022

Glycocalyx mechanotransduction mechanisms are involved in renal cancer metastasis.

Matrix biology plus

Moran H,Cancel LM,Huang P,Roberge S,Xu T,Tarbell JM,Munn LL

Tue Feb 01 00:00:00 UTC 2022

Parkinson's Disease Derived Exosomes Aggravate Neuropathology in SNCA*A53T Mice.

Annals of neurology

Huang Y,Liu Z,Li N,Tian C,Yang H,Huo Y,Li Y,Zhang J,Yu Z

Mon Aug 01 00:00:00 UTC 2022

Parkinson's Disease Derived Exosomes Aggravate Neuropathology in SNCA*A53T Mice.

Annals of neurology

Huang Y,Liu Z,Li N,Tian C,Yang H,Huo Y,Li Y,Zhang J,Yu Z

Mon Aug 01 00:00:00 UTC 2022

N-Glycans and sulfated glycosaminoglycans contribute to the action of diverse Tc toxins on mammalian cells.

PLoS pathogens

Song N,Chen L,Ren X,Waterfield NR,Yang J,Yang G

Mon Feb 01 00:00:00 UTC 2021

Bioinformatics

Protein Aliases: [Heparan sulfate]-glucosamine N-sulfotransferase 1; Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1; Glucosaminyl N-deacetylase/N-sulfotransferase 1; Golgi heparan sulfate N-deacetylase/N-sulfotransferase; heparan sulfate-N-deacetylase/N-sulfotransferase; heparan sulfate/heparin GlcNAc N-deacetylase/GlcN N-sulfotransferase 1; HSNST 1; N-Deacetylase-N-sulfotransferase 1; N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1; N-deacetylase/N-sulfotransferase 1; N-deacetylase/N-sulfotransferase-1; N-heparan sulfate sulfotransferase 1; N-HSST; N-HSST 1; NDST-1

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Gene Aliases: 1200015G06Rik; b2b2230Clo; HSST; HSST1; MRT46; NDST-1; NDST1; NST1

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UniProt ID: (Human) P52848, (Rat) Q02353, (Mouse) Q3UHN9

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Entrez Gene ID: (Human) 3340, (Rat) 29633, (Mouse) 15531

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Function(s)

Process(es)

MAPK cascade polysaccharide biosynthetic process protein sulfation inflammatory response smoothened signaling pathway respiratory gaseous exchange fibroblast growth factor receptor signaling pathway organ morphogenesis heparan sulfate proteoglycan biosynthetic process glycosaminoglycan metabolic process heparin biosynthetic process forebrain development midbrain development embryonic neurocranium morphogenesis embryonic viscerocranium morphogenesis cardiac septum development glycosaminoglycan biosynthetic process aorta development coronary vasculature development protein deacetylation metabolic process embryo development

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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NDST1 Polyclonal Antibody

NDST1 Antibody (26203-1-AP) in WB

Product Details

26203-1-AP

Western Blot (WB)

Immunocytochemistry (ICC/IF)

Flow Cytometry (Flow)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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