Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Recommended positive controls: HepG2, Raji, mouse liver.
Predicted reactivity: Mouse (88%), Rat (90%), Sheep (89%), Rhesus Monkey (94%), Chimpanzee (100%), Bovine (89%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes a protein which is part of mitochondrial complex 1, part of the oxidative phosphorylation system in mitochondria. Complex 1 transfers electrons to ubiquinone from NADH which establishes a proton gradient for the generation of ATP. Mutations in this gene are associated with Leigh syndrome due to mitochondrial complex 1 deficiency. Pseudogenes of this gene are located on chromosomes 5 and 13. Alternative splicing results in multiple transcript variants.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 13 kDa differentiation-associated protein; 13kDa differentiation-associated protein; CI-B17.2; CIB17.2; complex I B17.2 subunit; Complex I-B17.2; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12; NADH-ubiquinone oxidoreductase subunit B17.2
Gene Aliases: 2410011G03Rik; AW112974; B17.2; DAP13; NDUFA12; RGD1311462
UniProt ID: (Human) Q9UI09, (Mouse) Q7TMF3
Entrez Gene ID: (Human) 55967, (Rat) 299739, (Mouse) 66414
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