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Immunogen sequence: GAQCDKPNKE FMLCRWEEKD PRRCLEEGKL VNKCALDFFR QIKRHCAEPF TEYWTCIDYT GQQLFRHCRK QQAKFDECVL DKLGWVRPDL GELSKVTKVK TDRPLPENPY HSRPRPDPSP EIEGDLQPAT HGSRFYFWTK; Positive Samples: 293T, LO2, MCF7, Mouse heart, Mouse brain, Rat heart; Cellular Location: Mitochondrion inner membrane, Mitochondrion intermembrane space, Peripheral membrane protein
NDUFA8 is an accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Mammalian complex I is composed of 45 different subunits and transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CI-19kD; CI-PGIV; Complex I-19kD; Complex I-PGIV; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8; NADH-ubiquinone oxidoreductase 19 kDa subunit; NADH:ubiquinone oxidoreductase PGIV subunit
Gene Aliases: 0610033L03Rik; Aa2-258; AW261656; CI-19KD; CI-PGIV; NDUFA8; PGIV
UniProt ID: (Human) P51970, (Mouse) Q9DCJ5
Entrez Gene ID: (Human) 4702, (Mouse) 68375, (Rat) 296658
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