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Proteintech
NDUFS6 Monoclonal Antibody (2F4H3)
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Product Details
68329-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Chicken,
Human,
Mouse,
Rabbit,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
2F4H3
Immunogen
Recombinant protein
Conjugate
Form
Liquid
Purification
Protein G
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: MAAAMTFCRL LNRCGEAARS LPLGARCFGV RVSPTGEKVT HTGQVYDDKD YRRIRFVGRQ KEVNENFAID LIAEQPVSEV ETRVIACDGG GGALGHPKVY INLDKETKTG TCGYCGLQFR QHHH
Target Information
This gene encodes a subunit of the NADH:ubiquinone oxidoreductase, which is the first enzyme complex in the electron transport chain of mitochondria. This complex functions in the transfer of electrons from NADH to the respiratory chain. The subunit encoded by this gene is one of seven subunits in the iron-sulfur protein fraction. Mutations in this gene cause mitochondrial complex I deficiency, a disease that causes a wide variety of clinical disorders, including neonatal disease and adult-onset neurodegenerative disorders.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CI-13kD-A; complex I 13kDa subunit A; complex I, mitochondrial respiratory chain, 13-kD subunit; Complex I-13kD-A; NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase); NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase)-like; NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial; NADH dehydrogenase Fe-S protein 6; NADH ubiquinone oxidoreductase; NADH-ubiquinone oxidoreductase 13 kDa-A subunit; NADH:ubiquinone oxidoreductase NDUFS6 subunit
Gene Aliases: BC059730; CI-13kA; CI-13kD-A; CI13KDA; IP13; Ip13dis; Ndub13; NDUFS6; RATIp13dis
UniProt ID: (Human) O75380, (Mouse) P52503
Entrez Gene ID: (Rabbit) 100345307, (Human) 4726, (Mouse) 407785, (Rat) 29478
fatty acid metabolic process
transport
muscle contraction
multicellular organism aging
respiratory electron transport chain
multicellular organism growth
oxidation-reduction process
reproductive system development
mitochondrion morphogenesis
cardiovascular system development
biological_process
mitochondrial electron transport, NADH to ubiquinone
mitochondrial respiratory chain complex I assembly
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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