Proteintech

NDUFS7 Polyclonal Antibody

NDUFS7 Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 6

NDUFS7 Antibody (15728-1-AP) in ICC/IF

Immunofluorescent analysis of Hela cells, using NDUFS7 antibody 15728-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IGG (red).

NDUFS7 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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Product Details

15728-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:4,000

View 7 publications 7 publications

Immunohistochemistry (IHC)

View 2 publications 2 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunocytochemistry (ICC/IF)

1:10-1:100

View 3 publications 3 publications

Immunoprecipitation (IP)

Assay-dependent

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

NDUFS7 Fusion Protein Ag8471 (1-213 aa encoded by BC005954)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.29 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MAVLSAPGL RGFRILGLRS SVGLAVQARG VHQSVATDGP SSTQPALPKA RAVAPKPSSR GEYVVAKLDD LVNWARRSSL WPMTFGLACC AVEMMHMAAP RYDMDRFGVV FRASPRQSDV MIVAGTLTNK MAPALRKVYD QMPEPRYVVS MGSCANGGGY YHYSYSVVRG CDRIVPVDIY IPGCPPTAEA LLYGILQLQR KIKRERRLQI WYRR (1-213 aa encoded by BC005954)

Target Information

This gene encodes a protein that is a subunit of one of the complexes that forms the mitochondrial respiratory chain. This protein is one of over 40 subunits found in complex I, the nicotinamide adenine dinucleotide (NADH):ubiquinone oxidoreductase. This complex functions in the transfer of electrons from NADH to the respiratory chain, and ubiquinone is believed to be the immediate electron acceptor for the enzyme. Mutations in this gene cause Leigh syndrome due to mitochondrial complex I deficiency, a severe neurological disorder that results in bilaterally symmetrical necrotic lesions in subcortical brain regions.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

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NPJ precision oncology

Ye SB,Cheng YK,Li PS,Zhang L,Zhang LH,Huang Y,Chen P,Wang Y,Wang C,Peng JH,Shi LS,Ling L,Wu XJ,Qin J,Yang ZH,Lan P

Wed May 31 00:00:00 UTC 2023

Serine protease HtrA2/Omi regulates adaptive mitochondrial reprogramming in the brain cortex after ischemia/reperfusion injury via UCP2-SIRT3-PGC1 axis.

Human cell

Meng H,Sun LK,Su J,Yan WY,Jin Y,Luo X,Jiang XR,Wang HL

Sat Jan 01 00:00:00 UTC 2022

Metabolic targeting of cancer by a ubiquinone uncompetitive inhibitor of mitochondrial complex I.

Cell chemical biology

Jain S,Hu C,Kluza J,Ke W,Tian G,Giurgiu M,Bleilevens A,Campos AR,Charbono A,Stickeler E,Maurer J,Holinski-Feder E,Vaisburg A,Bureik M,Luo G,Marchetti P,Cheng Y,Wolf DA

Thu Mar 17 00:00:00 UTC 2022

Maintaining Iron Homeostasis Is the Key Role of Lysosomal Acidity for Cell Proliferation.

Molecular cell

Weber RA,Yen FS,Nicholson SPV,Alwaseem H,Bayraktar EC,Alam M,Timson RC,La K,Abu-Remaileh M,Molina H,Birsoy K

Thu Feb 06 00:00:00 UTC 2020

miR-142 controls metabolic reprogramming that regulates dendritic cell activation.

The Journal of clinical investigation

Sun Y,Oravecz-Wilson K,Bridges S,McEachin R,Wu J,Kim SH,Taylor A,Zajac C,Fujiwara H,Peltier DC,Saunders T,Reddy P

Mon Apr 08 00:00:00 UTC 2019

NDUFAB1 confers cardio-protection by enhancing mitochondrial bioenergetics through coordination of respiratory complex and supercomplex assembly.

Cell research

Hou T,Zhang R,Jian C,Ding W,Wang Y,Ling S,Ma Q,Hu X,Cheng H,Wang X

Sun Sep 01 00:00:00 UTC 2019

TRMT1-Catalyzed tRNA Modifications Are Required for Redox Homeostasis To Ensure Proper Cellular Proliferation and Oxidative Stress Survival.

Molecular and cellular biology

Dewe JM,Fuller BL,Lentini JM,Kellner SM,Fu D

Wed Nov 01 00:00:00 UTC 2017

TRMT1-Catalyzed tRNA Modifications Are Required for Redox Homeostasis To Ensure Proper Cellular Proliferation and Oxidative Stress Survival.

Molecular and cellular biology

Dewe JM,Fuller BL,Lentini JM,Kellner SM,Fu D

Wed Nov 01 00:00:00 UTC 2017

Altered Mitochondria, Protein Synthesis Machinery, and Purine Metabolism Are Molecular Contributors to the Pathogenesis of Creutzfeldt-Jakob Disease.

Journal of neuropathology and experimental neurology

Ansoleaga B,Garcia-Esparcia P,Llorens F,Hernández-Ortega K,Carmona Tech M,Antonio Del Rio J,Zerr I,Ferrer I

Mon Aug 01 00:00:00 UTC 2016

Altered Mitochondria, Protein Synthesis Machinery, and Purine Metabolism Are Molecular Contributors to the Pathogenesis of Creutzfeldt-Jakob Disease.

Journal of neuropathology and experimental neurology

Ansoleaga B,Garcia-Esparcia P,Llorens F,Hernández-Ortega K,Carmona Tech M,Antonio Del Rio J,Zerr I,Ferrer I

Mon Aug 01 00:00:00 UTC 2016

Human brain proteins showing neuron-specific interactions with γ-secretase.

The FEBS journal

Inoue M,Hur JY,Kihara T,Teranishi Y,Yamamoto NG,Ishikawa T,Wiehager B,Winblad B,Tjernberg LO,Schedin-Weiss S

Wed Jul 01 00:00:00 UTC 2015

Human brain proteins showing neuron-specific interactions with γ-secretase.

The FEBS journal

Inoue M,Hur JY,Kihara T,Teranishi Y,Yamamoto NG,Ishikawa T,Wiehager B,Winblad B,Tjernberg LO,Schedin-Weiss S

Wed Jul 01 00:00:00 UTC 2015

Identification of two novel synaptic γ-secretase associated proteins that affect amyloid β-peptide levels without altering Notch processing.

Neurochemistry international